Vibegron
What Is Vibegron ?[edit | edit source]
Vibegron (GEMTESA) is a beta-3 adrenergic agonist.
What are the uses of this medicine?[edit | edit source]
- This medication is indicated for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults.
How does this medicine work?[edit | edit source]
- Vibegron is a selective human beta-3 adrenergic receptor agonist.
- Activation of the beta-3 adrenergic receptor increases bladder capacity by relaxing the detrusor smooth muscle during bladder filling.
Who Should Not Use this medicine ?[edit | edit source]
This medicine cannot be used in:
- In patients with known hypersensitivity to vibegron or any components of the product
Is this medicine FDA approved?[edit | edit source]
- It was approved for use in the United States in 2020.
How should this medicine be used?[edit | edit source]
- The recommended dosage of GEMTESA is one 75 mg tablet orally, once daily with or without food.
- Swallow GEMTESA tablets whole with a glass of water.
- In adults, GEMTESA tablets also may be crushed, mixed with a tablespoon (approximately 15 mL) of applesauce and taken immediately with a glass of water.
What are the dosage forms and brand names of this medicine?[edit | edit source]
This medicine is available in fallowing dosage form:
- 75 mg tablets
This medicine is available in fallowing brand namesː GEMTESA
What side effects can this medication cause?[edit | edit source]
Common possible side effects of this medicine include:
- headache
- urinary tract infection
- nasopharyngitis
- diarrhea
- nausea
- upper respiratory tract infection
What special precautions should I follow?[edit | edit source]
- Urinary retention has been reported in patients taking GEMTESA.
- Monitor patients for signs and symptoms of urinary retention.
- Discontinue GEMTESA in patients who develop urinary retention.
What to do in case of emergency/overdose?[edit | edit source]
- There is no experience with inadvertent GEMTESA overdosage.
- In case of suspected overdose, treatment should be symptomatic and supportive.
Can this medicine be used in pregnancy?[edit | edit source]
- There are no available data on GEMTESA use in pregnant women.
Can this medicine be used in children?[edit | edit source]
- The safety and effectiveness of GEMTESA in pediatric patients have not been established.
What should I know about storage and disposal of this medication?[edit | edit source]
- Store at 20°C to 25°C (68°F to 77°F), excursions permitted to 15°C to 30°C (59°F to 86°F).
- Keep this and all medications out of sight and reach of children.
- Dispose unused medication via a take-back option if available; otherwise follow FDA instructions for disposal in the household trash.
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