CCL13
CCL13 (Chemokine (C-C motif) ligand 13) is a small cytokine belonging to the CC chemokine family that is also known as Monocyte Chemoattractant Protein 4 (MCP-4). It is predominantly expressed in monocytes, lymphocytes, basophils, and eosinophils. CCL13 is known to play roles in immunoregulatory and inflammatory processes.
Function[edit]
CCL13 is involved in the recruitment of leukocytes to the site of inflammation. It is also known to induce the migration of monocytes, lymphocytes, basophils, and eosinophils towards the site of inflammation. The chemotactic activity of CCL13 is mediated by CCR2, CCR3, and CCR5.
Clinical significance[edit]
CCL13 has been implicated in various inflammatory diseases such as rheumatoid arthritis, asthma, and atopic dermatitis. It has also been associated with the progression of HIV.
See also[edit]
- Chemokine
- Cytokine
- Monocyte
- Lymphocyte
- Basophil
- Eosinophil
- Leukocyte
- CCR2
- CCR3
- CCR5
- Rheumatoid arthritis
- Asthma
- Atopic dermatitis
- HIV
| Cell signaling: cytokines | ||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| Cell signaling: cytokines | ||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| Immunology | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
This immunology-related article is a stub.
|
| Inflammation | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
 | This medical article is a stub. You can help WikiMD by expanding the page. |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
