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What is 14-Ethoxymetopon?[edit | edit source]

  • It is an opioid analog and it is a highly potent analgesic drug several hundred times more potent than morphine[1]
  • IUPAC Name: (4R,4aS,7aR,12bR)-4a-ethoxy-9-hydroxy-3,7a-dimethyl-1,2,4,5,6,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
  • InChI: InChI=1S/C20H25NO4/c1-4-24-20-8-7-15(23)18(2)19(20)9-10-21(3)14(20)11-12-5-6-13(22)17(25-18)16(12)19/h5-6,14,22H,4,7-11H2,1-3H3/t14-,18+,19+,20-/m1/s1
  • Canonical SMILES: CCOC12CCC(=O)C3(C14CCN(C2CC5=C4C(=C(C=C5)O)O3)C)C
  • Isomeric SMILES: CCO[C@@]12CCC(=O)[C@]3([C@@]14CCN([C@@H]2CC5=C4C(=C(C=C5)O)O3)C)C
  • Molecular formula: C20H25NO4
  • Molecular weight: 343.4 g·mol−1
  • Synonyms:

131575-04-7 CHEMBL1255022 DTXSID50157119 BDBM50326663 Morphinan-6-one, 4,5-epoxy-14-ethoxy-3-hydroxy-5,17-dimethyl-, (5alpha)- (4R,4aS,7aR,12bR)-4a-ethoxy-9-hydroxy-3,7a-dimethyl-1,2,4,5,6,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one [2]

References[edit | edit source]

  1. Fürst Z, Búzás B, Friedmann T, Schmidhammer H, Borsodi A (May 1993). "Highly potent novel opioid receptor agonist in the 14-alkoxymetopon series". European Journal of Pharmacology. 236 (2): 209–15 [1][2].
  2. National Center for Biotechnology Information (2021). PubChem Compound Summary for CID 14683796, 14-Ethoxymetopon. Retrieved August 3, 2021 from [3].


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