3-Fluoroamphetamine

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3-Fluoroamphetamine

3-Fluoroamphetamine (3-FA) is a synthetic compound belonging to the class of substituted amphetamines. It is a structural analog of amphetamine, with a fluorine atom substituted at the third position of the phenyl ring.

Chemical Structure and Properties[edit | edit source]

3-Fluoroamphetamine is chemically similar to other amphetamines, with the molecular formula C9H12FN. The presence of the fluorine atom in the para position of the phenyl ring distinguishes it from other amphetamines such as amphetamine and methamphetamine.

Pharmacology[edit | edit source]

3-Fluoroamphetamine acts as a central nervous system stimulant. It is believed to exert its effects by increasing the release of monoamine neurotransmitters such as dopamine, norepinephrine, and serotonin. The exact mechanism of action and the potency of 3-FA compared to other amphetamines are subjects of ongoing research.

Legal Status[edit | edit source]

The legal status of 3-Fluoroamphetamine varies by country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of approved medical use. In others, it may be considered a research chemical and not explicitly regulated.

Potential Uses[edit | edit source]

While 3-Fluoroamphetamine has no approved medical uses, it has been studied in research settings to understand its pharmacological properties and potential therapeutic applications. However, due to its stimulant effects and potential for abuse, it is primarily of interest in the context of substance abuse research.

Safety and Toxicity[edit | edit source]

The safety profile of 3-Fluoroamphetamine is not well-established. As with other stimulants, there are concerns about its potential for addiction, cardiovascular effects, and neurotoxicity. Users may experience side effects similar to those of other amphetamines, including increased heart rate, elevated blood pressure, and anxiety.

Related Compounds[edit | edit source]

3-Fluoroamphetamine is part of a broader class of fluorinated amphetamines, which includes compounds such as 4-Fluoroamphetamine (4-FA) and 2-Fluoroamphetamine (2-FA). These compounds share similar structural features but may differ in their pharmacological effects and legal status.

Related Pages[edit | edit source]


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Contributors: Prab R. Tumpati, MD