Β-Methylphenethylamine

Β-Methylphenethylamine‏‎ (also known as β-Me-PEA, BMPEA, or 1-amino-2-phenylpropane) is a trace amine and human metabolite of the amino acid phenylalanine by enzymatic decarboxylation. It is a stimulant of the central nervous system (CNS) and has a structure closely related to amphetamine.

History

Β-Methylphenethylamine was first synthesized in the early 20th century but its pharmacological properties were not well studied until the 21st century. It was discovered to be a metabolite of phenylalanine in the human body in 2012.

Pharmacology

Β-Methylphenethylamine is a central nervous system stimulant. It is believed to increase levels of norepinephrine and dopamine in the brain, similar to the action of amphetamines. However, the exact mechanism of action is not fully understood.

Use and Regulation

Β-Methylphenethylamine has been found in dietary supplements marketed for weight loss and athletic performance enhancement. However, its safety and efficacy for these uses have not been established. In many countries, including the United States, it is not approved for use in dietary supplements and its sale is illegal.

Health Risks

The health risks of β-Methylphenethylamine are not well studied. However, due to its structural similarity to amphetamines, it may carry similar risks, including addiction, cardiovascular problems, and neurological effects.

See Also

• Phenethylamine
• Amphetamine
• Dietary supplement

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