4-Fluoroisobutyrfentanyl
4-Fluoroisobutyrfentanyl (4-FIBF) is a potent opioid analgesic drug that is an analog of fentanyl. It is part of the fentanyl analogues, a group of synthetic opioids that vary in potency. 4-Fluoroisobutyrfentanyl is considered to be a powerful opioid because it is approximately 4 to 6 times more potent than morphine.
Chemistry[edit | edit source]
4-Fluoroisobutyrfentanyl is a fluorinated derivative of isobutyrfentanyl. The chemical structure of 4-Fluoroisobutyrfentanyl is C24H30FN3O2. It belongs to the class of organic compounds known as phenylpiperidines, which are compounds containing a phenylpiperidine skeleton, which consists of a piperidine bound to a phenyl group.
Pharmacology[edit | edit source]
As an opioid, 4-Fluoroisobutyrfentanyl acts on the mu-opioid receptor in the brain, which is the same receptor that drugs like morphine and fentanyl act on. This results in effects such as analgesia (pain relief), sedation, and euphoria. However, it also has the potential for serious side effects such as respiratory depression, which can be fatal.
Legal Status[edit | edit source]
Due to its potency and potential for abuse, 4-Fluoroisobutyrfentanyl is a controlled substance in many countries. In the United States, it is a Schedule I controlled substance under the Controlled Substances Act. This means it has a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD