Hydroxypethidine
Hydroxypethidine is a synthetic opioid that was developed in the mid-20th century. It is a derivative of pethidine (also known as meperidine), which is a widely used opioid analgesic. Hydroxypethidine has been studied for its potential use in the treatment of severe pain, but it is not currently marketed for medical use.
Chemistry[edit | edit source]
Hydroxypethidine is a 4-phenylpiperidine derivative, which is a structural class that includes other opioid drugs such as pethidine, methadone, and fentanyl. The chemical structure of hydroxypethidine includes a hydroxy group, which differentiates it from its parent compound, pethidine.
Pharmacology[edit | edit source]
As an opioid, hydroxypethidine acts on the mu-opioid receptor in the central nervous system. This receptor is involved in the perception of pain, and its activation by opioids results in analgesia. The exact pharmacological profile of hydroxypethidine is not well-studied, but it is likely to share many of the effects of other opioids, including analgesia, sedation, euphoria, and potential for dependence and addiction.
History and Development[edit | edit source]
Hydroxypethidine was first synthesized in the 1950s, around the same time as many other synthetic opioids. Despite its potential for use in pain management, it has not been widely adopted in clinical practice. The reasons for this are not entirely clear, but may relate to the availability of other, better-studied opioids.
Legal Status[edit | edit source]
The legal status of hydroxypethidine varies by country. In many jurisdictions, it is likely to be classified as a controlled substance due to its potential for abuse and addiction.
See Also[edit | edit source]
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