Prodilidine
Prodilidine is a synthetic opioid that was developed in the late 1970s. It is a potent analgesic drug that is structurally related to pethidine (also known as meperidine).
History[edit | edit source]
Prodilidine was first synthesized in 1977 by a team of researchers at the University of Alberta. The drug was developed as part of a research program aimed at discovering new analgesic drugs that would have fewer side effects than existing opioids.
Pharmacology[edit | edit source]
Prodilidine acts primarily as a mu-opioid receptor agonist. This means it binds to and activates the mu-opioid receptors in the brain, which are responsible for mediating the pain-relieving effects of opioids.
In addition to its analgesic effects, prodilidine also has some antitussive (cough-suppressing) properties. This is a common characteristic of many opioids.
Clinical Use[edit | edit source]
Prodilidine is used clinically for the management of moderate to severe pain. It is typically administered via intravenous injection.
Due to its potency and potential for abuse, prodilidine is classified as a Schedule II controlled substance in the United States. This means it is legally available for medical use, but its distribution is strictly controlled to prevent misuse.
Side Effects[edit | edit source]
Like all opioids, prodilidine can cause a range of side effects. These can include nausea, vomiting, constipation, and respiratory depression. In severe cases, overdose can lead to coma or death.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
