4-Phenylfentanyl

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4-Phenylfentanyl


4-Phenylfentanyl is a synthetic opioid that is a derivative of fentanyl. It is part of the phenylpiperidines class of opioids and is known for its potent analgesic properties.

History[edit | edit source]

4-Phenylfentanyl was first synthesized in the late 20th century, following the discovery and widespread use of its parent compound, fentanyl. Like other fentanyl derivatives, it was developed in an attempt to create opioids with increased potency and duration of action.

Pharmacology[edit | edit source]

As a synthetic opioid, 4-Phenylfentanyl acts primarily on the mu-opioid receptor. It has a high affinity for this receptor, which is responsible for the drug's analgesic effects. The exact potency of 4-Phenylfentanyl is not well-studied, but it is believed to be significantly more potent than morphine, the standard by which other opioids are often compared.

Effects[edit | edit source]

The effects of 4-Phenylfentanyl are similar to those of other opioids. These include pain relief, sedation, and euphoria. However, like all opioids, it also carries a risk of respiratory depression, dependence, and overdose.

Legal Status[edit | edit source]

The legal status of 4-Phenylfentanyl varies by country. In many places, it is a controlled substance due to its potential for abuse and dependence.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD