Isomethadol

Isomethadol

Isomethadol is a synthetic opioid that is chemically related to methadone. It is used in the treatment of opioid addiction and pain management.

Chemistry

Isomethadol, also known as iso-methadone, is a synthetic opioid that is structurally similar to methadone. It is a racemic mixture of two stereoisomers, levomethadone (L-isomer) and dextromethadone (D-isomer). The L-isomer is responsible for the majority of the opioid activity.

Pharmacology

Isomethadol acts primarily as a mu-opioid receptor agonist. It also has some activity at the kappa-opioid receptor and delta-opioid receptor. The drug has a high bioavailability and a long half-life, making it suitable for the treatment of opioid addiction and chronic pain.

Medical Use

Isomethadol is used in the treatment of opioid addiction. It helps to prevent withdrawal symptoms in patients who are addicted to opioids. It is also used in pain management, particularly for chronic pain conditions.

Side Effects

Like other opioids, isomethadol can cause a range of side effects. These can include nausea, vomiting, constipation, drowsiness, and respiratory depression. In severe cases, it can cause opioid overdose, which can be fatal.

Legal Status

In many countries, isomethadol is a controlled substance. This means that its use, possession, and distribution are regulated by law. In the United States, it is classified as a Schedule II controlled substance under the Controlled Substances Act.

See Also

• Methadone
• Opioid
• Opioid addiction
• Pain management