Noracymethadol
Noracymethadol is a synthetic opioid that is less commonly known but has significant importance in the field of pharmacology. It is a derivative of methadone, a widely used opioid for the treatment of opioid use disorder.
Chemistry[edit | edit source]
Noracymethadol, chemically known as 6-Noracetylmethadol, is a synthetic opioid and an active metabolite of levomethadyl acetate. It is structurally related to methadone, a synthetic opioid analgesic. Noracymethadol is a racemic mixture, meaning it contains equal amounts of two enantiomers.
Pharmacology[edit | edit source]
Noracymethadol exhibits its effects by acting as an agonist at the mu-opioid receptor. This receptor is a key site of action for most opioids, and its activation results in analgesic effects. Noracymethadol is also known to have a longer duration of action compared to methadone, which makes it a potential candidate for the treatment of opioid use disorder.
Clinical Use[edit | edit source]
While Noracymethadol is not currently used in clinical practice, its pharmacological profile suggests potential utility in the treatment of opioid use disorder. Its long duration of action could potentially reduce the frequency of dosing and the risk of withdrawal symptoms.
Legal Status[edit | edit source]
Noracymethadol is a Schedule I controlled substance in the United States, indicating that it has a high potential for abuse and no accepted medical use.
See Also[edit | edit source]
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