Cianergoline
A detailed overview of the pharmacological compound Cianergoline
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| Image | 250 | ||
| Identifiers
ATC Code DrugBank UNII KEGG ChEBI IUPAC Name |
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Cianergoline is a pharmacological compound that acts as a dopamine receptor agonist. It is primarily used in research settings to study its effects on the central nervous system and its potential therapeutic applications.
Pharmacology[edit | edit source]
Cianergoline is known to interact with dopamine receptors, particularly the D2 subtype. This interaction is believed to modulate neurotransmitter release and influence various physiological processes, including mood regulation, motor control, and endocrine function.
Mechanism of Action[edit | edit source]
Cianergoline exerts its effects by binding to dopamine receptors in the brain, mimicking the action of endogenous dopamine. This binding leads to the activation of intracellular signaling pathways that result in altered neuronal activity and neurotransmitter release.
Pharmacokinetics[edit | edit source]
The pharmacokinetic profile of Cianergoline includes hepatic metabolism and renal excretion. The exact bioavailability and half-life of the drug are not well-documented, but it is known to be administered orally.
Clinical Applications[edit | edit source]
While Cianergoline is not widely used in clinical practice, its role as a dopamine agonist makes it a candidate for research into conditions such as Parkinson's disease, prolactinoma, and other disorders associated with dopaminergic dysfunction.
Research and Development[edit | edit source]
Research on Cianergoline has focused on its potential to modulate dopaminergic pathways and its effects on prolactin secretion. Studies have explored its use in animal models to better understand its pharmacodynamics and potential therapeutic benefits.
Safety and Side Effects[edit | edit source]
As with other dopamine agonists, Cianergoline may cause side effects such as nausea, dizziness, and hypotension. Long-term use and high doses may lead to more serious effects, including impulse control disorders and cardiac valvulopathy.
Also see[edit | edit source]
| Receptor Ligands | |
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| Class | Not specified |
| Function | Not specified |
| Endogenous Ligands | None listed |
| Agonists | None listed |
| Antagonists | None listed |
| Partial Agonists | None listed |
| Inverse Agonists | None listed |
| Allosteric Modulators | None listed |
| Related Receptors | None listed |
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Contributors: Prab R. Tumpati, MD
