Fluoroamphetamine

Fluoroamphetamine (4-FA; 4-FMP; PAL-303; "Flux"), also known as para-fluoroamphetamine (PFA) is a psychoactive research chemical of the phenethylamine and substituted amphetamine chemical classes. It produces stimulant and entactogenic effects, and is described as being somewhat similar in effect to MDMA, but with a longer duration of effect, lower propensity for compulsive redosing, and less emphasis on the serotonin system.

Chemistry

Fluoroamphetamine is a synthetic molecule of the amphetamine family. Molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. Fluoroamphetamine contains additional substitutions at R4 of the phenyl ring with a fluorine atom. This fluorine atom at R4 of the phenyl ring is responsible for the molecule's increased potency.

Pharmacology

As with other stimulants, the chronic use of fluoroamphetamine can be considered moderately addictive with a high potential for abuse and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and withdrawal effects may occur if a person suddenly stops their usage.

Effects

The effects of fluoroamphetamine can be broken down into several components which progressively intensify proportional to dosage. In comparison to its contemporaries, it is considered to have a smoother, longer-lasting, more therapeutic, and less amphetamine-like effect profile.

Legal Status

The legal status of fluoroamphetamine varies widely by country. It is illegal in some countries, but is legal for research purposes in others.

See Also

• Amphetamine
• MDMA
• Stimulant
• Serotonin