Flector patch

Flector patch
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Legal status	Prescription only
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The Flector Patch is a topical nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of acute pain due to minor strains, sprains, and contusions. It contains the active ingredient diclofenac epolamine, which is a derivative of diclofenac, a widely used NSAID.

Pharmacology

Mechanism of Action

The Flector Patch works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. Prostaglandins are mediators of inflammation and pain. By reducing the production of prostaglandins, diclofenac decreases inflammation and alleviates pain.

Pharmacokinetics

When applied to the skin, diclofenac epolamine is absorbed into the underlying tissues. The patch provides a sustained release of the medication, allowing for localized treatment of pain. The systemic absorption of diclofenac from the patch is lower compared to oral formulations, which reduces the risk of systemic side effects.

Indications

The Flector Patch is indicated for the topical treatment of acute pain due to minor strains, sprains, and contusions. It is particularly useful in cases where oral NSAIDs are contraindicated or when localized treatment is preferred.

Contraindications

The use of the Flector Patch is contraindicated in patients with:

• Known hypersensitivity to diclofenac or any component of the patch
• History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs
• Active gastrointestinal bleeding or peptic ulcer disease
• Severe renal impairment

Adverse Effects

Common adverse effects of the Flector Patch include:

• Local skin reactions such as dermatitis, pruritus, and erythema
• Systemic effects such as headache, dizziness, and nausea are less common due to the lower systemic absorption.

Serious adverse effects, although rare, can include:

• Anaphylaxis
• Stevens-Johnson syndrome
• Hepatotoxicity

Usage and Administration

The Flector Patch should be applied to intact skin over the most painful area. The patch should be changed every 12 hours. It is important to wash hands after applying or removing the patch to avoid accidental contact with the eyes or mucous membranes.

Special Populations

Pregnancy and Lactation

The use of the Flector Patch during pregnancy, especially in the third trimester, is not recommended due to the risk of premature closure of the ductus arteriosus in the fetus. It is also not recommended during lactation as diclofenac is excreted in breast milk.

Pediatric Use

The safety and efficacy of the Flector Patch in pediatric patients have not been established.

Geriatric Use

Elderly patients may be at greater risk for adverse effects due to age-related decline in renal function and should use the patch with caution.

Drug Interactions

The Flector Patch may interact with other medications, including:

• Anticoagulants such as warfarin
• Other NSAIDs or aspirin
• Diuretics and antihypertensive agents

Storage

The Flector Patch should be stored at room temperature, away from moisture and heat. It should be kept out of reach of children and pets.

Conclusion

The Flector Patch is a valuable option for the localized treatment of acute pain due to minor injuries. Its topical application minimizes systemic exposure and reduces the risk of systemic side effects associated with oral NSAIDs.