PNU-142633

PNU-142633 is a drug that was developed by Pfizer for the treatment of migraine. It acts as a selective 5-HT1D receptor agonist, and has a strong analgesic effect, but has not been developed for medical use.

Pharmacology

PNU-142633 is a potent and selective agonist for the 5-HT1D receptor, which is a subtype of the serotonin receptor. This receptor is thought to be involved in the pathophysiology of migraine, and drugs that activate this receptor can have a strong analgesic effect.

Clinical trials

PNU-142633 has been tested in clinical trials for the treatment of migraine. However, it has not been developed for medical use, possibly due to side effects or lack of efficacy.

See also

• 5-HT1D receptor
• Serotonin receptor
• Migraine

References

PNU-142633 Resources
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