Carnosic acid
Carnosic acid is a natural benzenediol abietane diterpene found in rosemary and sage. It is a pro-antioxidant that is activated by metabolic transformation.
Chemistry[edit | edit source]
Carnosic acid is a polyphenolic compound with the molecular formula C20H28O4. It is a member of the class of compounds known as abietane diterpenoids. These are diterpenoids with a structure based on the abietane skeleton, which is a tricyclic diterpene in which the C4 and C8 methyl groups migrate to give a pimarane-type skeleton.
Biological Activity[edit | edit source]
Carnosic acid has been found to have antioxidant and anti-inflammatory properties. It has been studied for its potential benefits in neurodegenerative diseases, cancer, and diabetes. It has also been found to have antimicrobial activity against a variety of bacteria and fungi.
Health Benefits[edit | edit source]
Carnosic acid has been studied for its potential health benefits in a variety of areas. It has been found to have neuroprotective effects, potentially helping to protect against diseases such as Alzheimer's and Parkinson's. It has also been found to have anti-cancer properties, with studies showing it can inhibit the growth of certain types of cancer cells. In addition, it has been found to have anti-diabetic properties, potentially helping to improve insulin sensitivity and reduce blood sugar levels.
Safety and Toxicity[edit | edit source]
Carnosic acid is generally considered safe, with no known serious side effects. However, as with any supplement, it should be used under the supervision of a healthcare provider.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD