N-MPPP
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N-MPPP (N-methyl-1-(1-phenylpropan-2-yl)piperidine-4-carboxylic acid methyl ester) is a synthetic opioid analgesic drug. It is structurally related to MPPP, a known opioid analgesic, and is part of the piperidine class of compounds. N-MPPP is primarily of interest in the context of its pharmacological properties and potential for abuse.
Chemical Structure and Properties[edit | edit source]
N-MPPP is a piperidine derivative with the chemical formula C15H21NO2. It is characterized by the presence of a piperidine ring, a phenyl group, and a methyl ester functional group. The compound is typically synthesized through a series of chemical reactions involving the precursor chemicals such as phenylacetone and piperidine.
Pharmacology[edit | edit source]
N-MPPP acts as an agonist at the mu-opioid receptor, which is responsible for its analgesic effects. The activation of these receptors leads to the inhibition of neurotransmitter release, resulting in pain relief. However, like other opioids, N-MPPP has the potential for abuse and addiction due to its euphoric effects.
Synthesis[edit | edit source]
The synthesis of N-MPPP involves the reaction of phenylacetone with piperidine in the presence of a methylating agent. The process requires careful control of reaction conditions to avoid the formation of impurities, such as the neurotoxic compound MPTP, which can occur as a byproduct in the synthesis of related compounds.
Potential Risks and Toxicity[edit | edit source]
N-MPPP, like other synthetic opioids, carries a risk of overdose and respiratory depression. The compound's potential for abuse and addiction makes it a substance of concern in the context of public health. Additionally, improper synthesis can lead to the formation of toxic byproducts, which can cause severe neurological damage.
Legal Status[edit | edit source]
N-MPPP is classified as a controlled substance in many jurisdictions due to its potential for abuse and lack of accepted medical use. It is important for researchers and healthcare professionals to be aware of the legal restrictions surrounding this compound.
Also see[edit | edit source]
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