ATC code L02 Endocrine therapy is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.[1][2] Subgroup L02 is part of the anatomical group L Antineoplastic and immunomodulating agents.[3]
Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QL02.[4]
National issues of the ATC classification may include additional codes not present in this list, which follows the WHO version.
L02A Hormones and related agents[edit]
- L02AA01 Diethylstilbestrol
- L02AA02 Polyestradiol phosphate
- L02AA03 Ethinylestradiol
- L02AA04 Fosfestrol
- L02AB01 Megestrol
- L02AB02 Medroxyprogesterone
- L02AB03 Gestonorone
- L02AE01 Buserelin
- L02AE02 Leuprorelin
- L02AE03 Goserelin
- L02AE04 Triptorelin
- L02AE05 Histrelin
- L02AE51 Leuprorelin and bicalutamide
L02AX Other hormones[edit]
L02B Hormone antagonists and related agents[edit]
L02BA Anti-estrogens[edit]
- L02BA01 Tamoxifen
- L02BA02 Toremifene
- L02BA03 Fulvestrant
L02BB Anti-androgens[edit]
- L02BB01 Flutamide
- L02BB02 Nilutamide
- L02BB03 Bicalutamide
- L02BB04 Enzalutamide
- L02BB05 Apalutamide
- L02BG01 Aminogluthetimide
- L02BG02 Formestane
- L02BG03 Anastrozole
- L02BG04 Letrozole
- L02BG05 Vorozole
- L02BG06 Exemestane
L02BX Other hormone antagonists and related agents[edit]
- L02BX01 Abarelix
- L02BX02 Degarelix
- L02BX03 Abiraterone
References[edit]
| Androgens and antiandrogens |
Androgens
(incl. AAS
) | |
| Antiandrogens |
|
| AR
antagonists | |
Steroidogenesis
inhibitors | |
| Antigonadotropins | * D2 receptor antagonists ( prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
- Estrogens (e.g., bifluranol, diethylstilbestrol, estradiol, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
- GnRH agonists (e.g., leuprorelin)
- GnRH antagonists (e.g., cetrorelix)
- Progestogens (incl., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)
|
| Others | |
|
|
|
| Estrogens and antiestrogens |
| Estrogens |
|
| ER
agonists | * Steroidal: Alfatradiol
- Certain androgens/anabolic steroids (e.g., testosterone, testosterone esters, methyltestosterone, metandienone, nandrolone esters) (via estrogenic metabolites)
- Certain progestins (e.g., norethisterone, noretynodrel, etynodiol diacetate, tibolone)
- Clomestrone
- Cloxestradiol acetate
- Conjugated estriol
- Conjugated estrogens
- Epiestriol
- Epimestrol
- Esterified estrogens
- Estetrol†
- Estradiol
- Estradiol esters (e.g., estradiol acetate, estradiol benzoate, estradiol cypionate, estradiol enanthate, estradiol undecylate, estradiol valerate, polyestradiol phosphate, estradiol ester mixtures (Climacteron))
- Estramustine phosphate
- Estriol
- Estriol esters (e.g., estriol succinate, polyestriol phosphate)
- Estrogenic substances
- Estrone
- Estrone esters
- Ethinylestradiol#
- Hydroxyestrone diacetate
- Mestranol
- Methylestradiol
- Moxestrol
- Nilestriol
- Prasterone (dehydroepiandrosterone; DHEA)
- Promestriene
- Quinestradol
- Quinestrol
|
| Progonadotropins | |
|
|
| Antiestrogens |
|
ER
antagonists
(incl. SERMs
/SERDs
) | |
| Aromatase inhibitors | |
| Antigonadotropins | * Androgens/ anabolic steroids (e.g., testosterone, testosterone esters, nandrolone esters, oxandrolone, fluoxymesterone)
- D2 receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
- GnRH
agonists (e.g., leuprorelin, goserelin)
- GnRH
antagonists (e.g., cetrorelix, elagolix)
- Progestogens (e.g., chlormadinone acetate, cyproterone acetate, gestonorone caproate, hydroxyprogesterone caproate, medroxyprogesterone acetate, megestrol acetate)
|
| Others | * Mixed mechanism of action: Danazol
|
|
|
|
| GnRH
and gonadotropins |
GnRH
modulators
(incl. analogues) | |
| Gonadotropins | |
Others
(indirect) |
|
| Progonadotropins | |
| Antigonadotropins | * Sex steroid agonists (via negative feedback on the HPG
axis): Androgens/ anabolic steroids (e.g., testosterone, nandrolone esters, oxandrolone)
- D2 receptor antagonists (prolactin releasers) (incl., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
- Estrogens (incl., bifluranol, estradiol, estradiol esters, ethinylestradiol, diethylstilbestrol, paroxypropione)
- Progestogens (incl. progestins, e.g., chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate)
|
|
|
|
