OR2V2
OR2V2 is a gene that encodes the olfactory receptor, family 2, subfamily V, member 2 in humans. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.
Function[edit | edit source]
The OR2V2 gene is part of the olfactory receptor gene family, which is the largest gene family in the human genome. The proteins encoded by these genes are responsible for the recognition and transduction of odorant signals, which are mediated by G proteins. The OR2V2 gene specifically encodes the olfactory receptor, family 2, subfamily V, member 2.
Structure[edit | edit source]
The OR2V2 gene is located on chromosome 19q13.2 and is composed of a single coding exon. The encoded protein is a member of the G-protein-coupled receptor 1 family and has 7 transmembrane domains, a characteristic structure of many neurotransmitter and hormone receptors.
Clinical Significance[edit | edit source]
While the specific clinical significance of OR2V2 is not yet fully understood, olfactory receptors in general have been implicated in various diseases and conditions. For example, alterations in olfactory receptor function have been associated with anosmia, the inability to perceive odor. Additionally, olfactory receptors have been found to be expressed in a number of tissues outside of the olfactory system, suggesting potential roles in various physiological and pathological processes.
See Also[edit | edit source]
References[edit | edit source]
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