OR51S1

OR51S1 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors which are responsible for detecting molecules in the environment and subsequently initiating a neuronal response. The olfactory receptor proteins interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell.

Function

The olfactory receptor family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. The OR51S1 gene is a member of the olfactory receptor family, and like other members of this family, it is believed to play a role in the detection of environmental chemicals and the initiation of sensory responses.

Structure

The OR51S1 gene is located on chromosome 11, and it spans approximately 1,000 base pairs. The encoded protein is a member of the G protein-coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and function in signal transduction from the outside of the cell to the inside.

Clinical Significance

While the specific function of OR51S1 is not yet fully understood, it is believed to play a role in olfaction, the sense of smell. Mutations in this gene could potentially impact the sense of smell, although more research is needed to fully understand the clinical significance of this gene.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Signal transduction
• Olfaction