OR4F6

OR4F6 is a gene that in humans is encoded by the OR4F6 olfactory receptor family 4 subfamily F member 6. The olfactory receptor genes are the largest gene family in mammals. They are G protein-coupled receptors that detect odor molecules in the nose and participate in the perception of smell. They are expressed in the cilia of olfactory sensory neurons.

Function

The OR4F6 gene is a member of the olfactory receptor gene family. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Clinical significance

While the specific function and clinical significance of OR4F6 is not yet fully understood, olfactory receptors in general are known to play a crucial role in human health and disease. They are involved in various physiological processes such as food intake, social behavior, and fertility. Abnormalities in olfactory function can lead to conditions such as anosmia (loss of the sense of smell) and hyposmia (reduced ability to smell).

See also

• Olfactory receptor
• Anosmia
• Hyposmia

External links

• OR4F6 at the National Center for Biotechnology Information