OR10G3

OR10G3 is a gene that encodes a protein in the olfactory receptor family. This family is a group of G protein-coupled receptors which are involved in detecting odors and pheromones. The OR10G3 gene is specifically expressed in the olfactory epithelium, a specialized tissue inside the nose that is involved in smell.

Structure

The OR10G3 gene is located on chromosome 1, specifically at 1q44. It spans approximately 1.1 kilobases and consists of a single exon. The encoded protein is 312 amino acids in length. Like other olfactory receptors, OR10G3 is a seven-transmembrane domain protein that couples to a G protein to signal the presence of a specific odorant molecule.

Function

The exact function of OR10G3 is not well understood, as is the case for many olfactory receptors. However, it is known that the protein it encodes is involved in the detection of odorants. When an odorant molecule binds to the OR10G3 receptor, it triggers a signal transduction pathway that ultimately leads to the perception of smell.

Clinical significance

While the OR10G3 gene is not currently associated with any specific diseases, mutations in olfactory receptor genes in general can lead to a reduced sense of smell, a condition known as anosmia. Further research is needed to determine the specific role of OR10G3 in human health and disease.

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

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