JWH-103
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JWH-103 is a synthetic cannabinoid from the naphthoylindole family, which acts as a potent agonist at the cannabinoid receptors. It was developed by John W. Huffman and his team at Clemson University as part of research into the structure-activity relationships of cannabinoids.
Chemical Structure and Properties[edit | edit source]
JWH-103 is chemically classified as a naphthoylindole, which is a subclass of synthetic cannabinoids. Its structure is characterized by a naphthyl group attached to an indole core, which is a common feature in many synthetic cannabinoids. The chemical formula of JWH-103 is C24H28O, and it has a molecular weight of 332.48 g/mol.
Pharmacology[edit | edit source]
JWH-103 acts as a full agonist at both the CB1 and CB2 cannabinoid receptors. These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes such as pain sensation, mood, and appetite. The binding affinity of JWH-103 for these receptors is similar to that of other synthetic cannabinoids, making it a potent compound in this class.
Legal Status[edit | edit source]
The legal status of JWH-103 varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of medical use. It is often included in legislation targeting synthetic cannabinoids and "designer drugs."
Research and Applications[edit | edit source]
JWH-103, like other synthetic cannabinoids, has been used in scientific research to study the endocannabinoid system and to develop potential therapeutic agents. However, due to its psychoactive effects and potential for abuse, its use is restricted to laboratory settings.
Health Effects and Risks[edit | edit source]
The health effects of JWH-103 are not well-documented, but it is expected to have similar effects to other synthetic cannabinoids, which can include euphoria, altered perception, and in some cases, anxiety or paranoia. The long-term health effects are unknown, and there is a risk of toxicity and adverse reactions.
Also see[edit | edit source]
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