1-Pentyl-3-(2-methoxybenzoyl)indole

1-Pentyl-3-(2-methoxybenzoyl)indole is a synthetic cannabinoid that belongs to the indole family of compounds. It is often used in scientific research to study the effects of cannabinoids on the human body. This compound is structurally related to other synthetic cannabinoids that have been used in the formulation of designer drugs.

Chemical Structure and Properties

1-Pentyl-3-(2-methoxybenzoyl)indole is characterized by its indole core, which is a bicyclic structure consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. The compound has a pentyl chain attached to the nitrogen atom of the indole, and a 2-methoxybenzoyl group attached to the third position of the indole ring.

Molecular Formula

The molecular formula of 1-Pentyl-3-(2-methoxybenzoyl)indole is C21H25NO2.

Molecular Weight

The molecular weight of this compound is 323.43 g/mol.

Chemical Identifiers

• CAS Number: 155471-08-2
• PubChem CID: 444693

Pharmacology

1-Pentyl-3-(2-methoxybenzoyl)indole acts as an agonist at the cannabinoid receptors, primarily the CB1 and CB2 receptors. These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes including pain sensation, mood, and appetite.

Mechanism of Action

As a synthetic cannabinoid, 1-Pentyl-3-(2-methoxybenzoyl)indole mimics the action of naturally occurring cannabinoids such as tetrahydrocannabinol (THC), the active component of cannabis. It binds to the cannabinoid receptors in the brain and other parts of the body, leading to altered neurotransmitter release and modulation of synaptic transmission.

Legal Status

The legal status of 1-Pentyl-3-(2-methoxybenzoyl)indole varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use.

Safety and Toxicology

The safety profile of 1-Pentyl-3-(2-methoxybenzoyl)indole is not well-established, and its use is associated with potential adverse effects similar to those of other synthetic cannabinoids. These may include tachycardia, hypertension, anxiety, and hallucinations.

Research Applications

This compound is primarily used in research settings to study the effects of synthetic cannabinoids on the central nervous system and to develop potential therapeutic agents targeting the endocannabinoid system.

Also see

• Synthetic cannabinoids
• Cannabinoid receptor
• Endocannabinoid system
• Designer drugs