O-1184

O-1184 is a synthetic compound that has been studied for its potential pharmacological effects, particularly in the field of cannabinoid receptor research. It is a member of a class of compounds known as cannabinoid receptor agonists, which interact with the endocannabinoid system in the body.

Chemical Structure and Properties

O-1184 is a chemical analog of other well-known cannabinoids, but it has been modified to enhance its selectivity and potency at specific cannabinoid receptors. The exact chemical structure of O-1184 includes a core structure that is common to many cannabinoids, with specific functional groups that confer its unique properties.

Pharmacology

O-1184 acts primarily as an agonist at the CB1 receptor, which is one of the two main types of cannabinoid receptors found in the body. The CB1 receptor is predominantly located in the central nervous system, and its activation is associated with a variety of effects, including modulation of neurotransmitter release, pain perception, and appetite.

Mechanism of Action

The mechanism of action of O-1184 involves binding to the CB1 receptor, leading to a conformational change that activates intracellular signaling pathways. This activation can result in the inhibition of adenylate cyclase, modulation of ion channels, and activation of mitogen-activated protein kinases (MAPKs).

Therapeutic Potential

Research into O-1184 has suggested potential therapeutic applications in areas such as pain management, neurological disorders, and appetite regulation. However, further studies are needed to fully understand its efficacy and safety profile.

Research and Development

O-1184 is still under investigation, and much of the research is preclinical. Studies have focused on its pharmacokinetics, receptor binding affinity, and potential therapeutic effects in animal models.

Safety and Toxicology

The safety profile of O-1184 is not yet fully established. Preliminary studies suggest that it may have a similar side effect profile to other cannabinoid receptor agonists, which can include dizziness, dry mouth, and changes in mood or perception.

Legal Status

As of the latest updates, O-1184 is not approved for medical use and is primarily used in research settings. Its legal status may vary by country, and it is important for researchers to comply with local regulations regarding its use.

Also see

• Cannabinoid receptor
• Endocannabinoid system
• CB1 receptor
• Cannabinoid receptor agonists
• Pain management