HU-910

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HU-910_structure.png



HU-910 is a synthetic cannabinoid that has been studied for its potential therapeutic effects. It is a derivative of tetrahydrocannabinol (THC), the primary psychoactive component of Cannabis. HU-910 is part of a series of synthetic cannabinoids developed to explore the structure-activity relationships of cannabinoids and their potential medical applications.

Chemical Structure and Properties[edit | edit source]

HU-910 is chemically classified as a cannabinoid, specifically a derivative of Δ⁸-tetrahydrocannabinol. Its chemical structure is characterized by the presence of a dimethylheptyl side chain, which is known to enhance the potency and duration of action compared to natural THC. The compound also features an 11-hydroxy group, which is a common modification in synthetic cannabinoids to increase their affinity for cannabinoid receptors.

Pharmacology[edit | edit source]

HU-910 acts primarily as an agonist at the cannabinoid receptor type 1 (CB1) and cannabinoid receptor type 2 (CB2). These receptors are part of the endocannabinoid system, which plays a role in regulating various physiological processes including pain, mood, appetite, and memory. The activation of CB1 receptors by HU-910 is associated with its psychoactive effects, while CB2 receptor activation is linked to its potential anti-inflammatory and immunomodulatory properties.

Potential Therapeutic Applications[edit | edit source]

Research into HU-910 has suggested several potential therapeutic applications:

  • Pain Management: Due to its interaction with the endocannabinoid system, HU-910 may be effective in managing chronic pain conditions.
  • Anti-inflammatory Effects: The activation of CB2 receptors suggests potential use in treating inflammatory diseases.
  • Neuroprotection: Studies indicate that cannabinoids like HU-910 may offer neuroprotective benefits, potentially useful in conditions such as Alzheimer's disease and Parkinson's disease.

Research and Development[edit | edit source]

As a research chemical, HU-910 is primarily studied in preclinical settings. Its development is part of ongoing efforts to create synthetic cannabinoids that can be used safely and effectively in medical treatments. However, due to its status as a synthetic cannabinoid, it is subject to regulatory scrutiny and is not approved for clinical use in humans.

Safety and Legal Status[edit | edit source]

The safety profile of HU-910 is not well-established, as it is still under investigation. Like other synthetic cannabinoids, it may pose risks of adverse effects, particularly at high doses. Its legal status varies by country, with some jurisdictions classifying it as a controlled substance due to its potential for abuse and psychoactive effects.

Also see[edit | edit source]


Template:Receptor ligands

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Contributors: Prab R. Tumpati, MD