Morphine

From WikiMD's Wellness Encyclopedia

(Redirected from Ms Contin)

Information about Morphine[edit source]

Morphine is one of the natural plant alkaloids found in opium and is the prototype opiate, against which other derivatives are measured in terms of analgesic effects and side effects.

Morphine

Liver safety of Morphine[edit source]

Morphine has not been linked to serum enzyme elevations during therapy or to clinically apparent liver injury.

Mechanism of action of Morphine[edit source]

Morphine is a natural alkaloid that is derived from resin extracts from the seeds of the opium poppy, Papaver somniferum. Morphine has potent and profound analgesic effects and has been used in clinical medicine for almost two hundred years. Morphine acts by engagement in cell surface opiate receptors (predominant µ type receptors) that are found in the central nervous system, but also heart, lung, vascular and intestinal cells. Current indications are for severe pain, pre- and postoperative analgesia, control of pain from angina pectoris or acute myocardial infarction and therapy of pulmonary edema.

Dosage and administration for Morphine[edit source]

Morphine is available in multiple formulations, including oral tablets and syrups, suppositories, and solutions for injection in multiple concentrations. The typical dose of morphine for analgesia in adults is 10 mg every 3 to 4 hours by the subcutaneous, intramuscular or intravenous route. Morphine is well absorbed orally, but has extensive and variable first pass metabolism, so that its effect orally is somewhat variable.

Side effects of Morphine[edit source]

Side effects of opiates are many and include sedation, respiratory depression, confusion, euphoria, agitation, itching, abdominal bloating, nausea, vomiting and diarrhea.

DEA controlled substance classification of Morphine[edit source]

Morphine is a controlled substance and classified as a Schedule II drug, indicating that it has medical usefulness, but also a high potential for physical and psychological dependency and abuse. Full and partial opiod agonists:

Opiate antagonists:

Morphine Resources
Wikipedia





WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Retrieved from "https://wikimd.com/w/index.php?title=Morphine&oldid=4959811"

Contributors: Prab R. Tumpati, MD