Tebipenem pivoxil

Tebipenem pivoxil is an antibiotic that belongs to the carbapenem class of antibiotics. It is a prodrug of tebipenem, and is primarily used in the treatment of bacterial infections.

Pharmacology

Tebipenem pivoxil is a prodrug, which means it is inactive in its ingested form and is metabolized into its active form, tebipenem, in the body. The active form of the drug works by inhibiting the synthesis of the bacterial cell wall, leading to the death of the bacteria.

Medical uses

Tebipenem pivoxil is used to treat a variety of bacterial infections, including respiratory tract infections, urinary tract infections, and skin and soft tissue infections. It is effective against a wide range of bacteria, including both Gram-positive and Gram-negative organisms.

Side effects

Like all antibiotics, tebipenem pivoxil can cause side effects. The most common side effects include nausea, vomiting, diarrhea, and rash. In rare cases, it can cause more serious side effects such as allergic reactions and C. difficile infection.

History

Tebipenem pivoxil was first approved for medical use in Japan in 2009. It is marketed under the brand name Orapenem by Meiji Seika.

See also

• List of antibiotics
• Carbapenem
• Prodrug

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