5-Methoxy-7,N,N-trimethyltryptamine

5-Methoxy-7,N,N-trimethyltryptamine is a psychedelic and hallucinogenic compound of the tryptamine class. It is a structural and functional analog of other psychedelic tryptamines such as 5-MeO-DMT, 5-HO-DMT, and DMT.

Chemistry

5-Methoxy-7,N,N-trimethyltryptamine is a tryptamine derivative and shares a common structural feature with other tryptamines, which is a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. However, 5-Methoxy-7,N,N-trimethyltryptamine is unique among the tryptamines due to its substitution at the 7 position of the indole ring with a methoxy (OCH3) group. It also has three methyl groups (CH3) attached to the nitrogen (N) of the amino group, hence the name 7,N,N-trimethyltryptamine.

Pharmacology

The pharmacological actions of 5-Methoxy-7,N,N-trimethyltryptamine are not fully understood. However, like other tryptamines, it is thought to act primarily as a serotonin receptor agonist. It may also interact with other neurotransmitter systems. The presence of the methoxy group at the 7 position of the indole ring may confer unique pharmacological properties compared to other tryptamines.

Effects

The effects of 5-Methoxy-7,N,N-trimethyltryptamine can vary greatly depending on the dose and individual's physiology. Common effects reported include visual hallucinations, altered perception of time and space, euphoria, and spiritual experiences. However, negative effects such as anxiety, paranoia, and dangerous physiological responses can also occur.

Legal Status

The legal status of 5-Methoxy-7,N,N-trimethyltryptamine varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use.

See Also

• Tryptamine
• Psychedelic drug
• Hallucinogen
• Serotonin receptor