Gastroesophageal junction

Gastroesophageal junction is the area where the esophagus and the stomach meet. This junction is important in the body's digestive system and plays a crucial role in preventing acid reflux.

Anatomy

The gastroesophageal junction is located at the lower end of the esophagus and the upper part of the stomach. It is a tight ring of muscles that acts as a valve to control the flow of food and liquid from the esophagus to the stomach. This valve is also known as the lower esophageal sphincter (LES).

Function

The primary function of the gastroesophageal junction is to prevent the backward flow of stomach contents, including gastric acid, into the esophagus. When food or liquid is swallowed, the LES relaxes to allow the food or liquid to pass into the stomach and then contracts again to prevent reflux.

Disorders

Disorders of the gastroesophageal junction include gastroesophageal reflux disease (GERD), Barrett's esophagus, and esophageal cancer. These conditions can cause symptoms such as heartburn, chest pain, and difficulty swallowing.

Gastroesophageal Reflux Disease

GERD is a condition in which the LES does not function properly, allowing stomach acid to flow back into the esophagus. This can cause damage to the esophageal lining and result in heartburn and other symptoms.

Barrett's Esophagus

Barrett's esophagus is a condition in which the cells lining the lower esophagus change or are replaced with abnormal cells. This condition can increase the risk of developing esophageal cancer.

Esophageal Cancer

Esophageal cancer is a type of cancer that occurs in the esophagus. It can develop in any part of the esophagus, but it is more common in the lower part near the gastroesophageal junction.

See Also

• Esophagus
• Stomach
• Gastroesophageal reflux disease
• Barrett's esophagus
• Esophageal cancer

Gastroesophageal junction Resources
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