Hydromorphone hydrochloride

Hydromorphone hydrochloride is a narcotic analgesic used in the treatment of moderate to severe pain. It is a derivative of morphine and is commonly used in the medical field for its potent pain relieving effects.

Pharmacology

Hydromorphone hydrochloride acts on the central nervous system and smooth muscle tissue, slowing the central nervous system. It binds to the mu-opioid receptor, which is responsible for the drug's analgesic effects.

Uses

Hydromorphone hydrochloride is used to treat moderate to severe pain. It is also used as a cough suppressant in smaller doses.

Side Effects

Common side effects of hydromorphone hydrochloride include nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, sweating, flushing, and mood changes. Serious side effects can include slow/shallow breathing, seizures, and a condition known as serotonin syndrome.

Precautions

Patients with a history of allergy to hydromorphone, morphine, or other opioid medications should not use hydromorphone hydrochloride. It should also be used with caution in patients with a history of respiratory depression, head injury, brain tumor, severe asthma, or hypotension.

Interactions

Hydromorphone hydrochloride can interact with other medications, including benzodiazepines, antidepressants, antipsychotics, and alcohol. These interactions can increase the risk of respiratory depression, sedation, and death.

See Also

• Opioid
• Analgesic
• Morphine

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