Phendimetrazine tartrate

Phendimetrazine tartrate is a pharmaceutical drug used primarily as an appetite suppressant in the treatment of obesity. It is a sympathomimetic amine, which is similar to an amphetamine. Phendimetrazine tartrate stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Pharmacology

Phendimetrazine tartrate is a phenylalkylamine derivative which functions as a norepinephrine releasing agent. It is structurally similar to amphetamine, but the primary site of action is believed to be in the cortex of the brain rather than the hypothalamus. The drug is also a serotonin releasing agent to a lesser extent.

Medical Uses

Phendimetrazine tartrate is used medically as an appetite suppressant for short term use, as part of a treatment plan for weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for patients with an initial body mass index greater than or equal to 30 kg/m2, or greater than or equal to 27 kg/m2 in the presence of other risk factors.

Side Effects

Common side effects of phendimetrazine tartrate include: dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to the medication. Other side effects include rapid breathing, unusual restlessness, a feeling of being unusually cold, and difficulty with walking.

See Also

• Anorectic
• Amphetamine
• Obesity