5'-DMH-CBD

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5'-DMH-CBD (5'-Dimethylheptyl-cannabidiol) is a synthetic analog of cannabidiol (CBD), a major non-psychoactive component of the Cannabis sativa plant. This compound is of interest in the field of pharmacology and medicinal chemistry due to its potential therapeutic properties.

Chemical Structure and Properties[edit | edit source]

5'-DMH-CBD is a derivative of cannabidiol, where the pentyl side chain of CBD is replaced with a dimethylheptyl group. This modification is intended to enhance the compound's lipophilicity and potentially its bioavailability. The chemical formula of 5'-DMH-CBD is C23H38O2, and it has a molecular weight of 346.55 g/mol.

Pharmacological Effects[edit | edit source]

5'-DMH-CBD has been studied for its effects on the endocannabinoid system, which plays a crucial role in regulating various physiological processes such as pain, inflammation, and immune response. Like CBD, 5'-DMH-CBD is believed to interact with cannabinoid receptors (CB1 and CB2) and may also influence other receptor systems such as serotonin and vanilloid receptors.

Potential Therapeutic Uses[edit | edit source]

Research into 5'-DMH-CBD is ongoing, but preliminary studies suggest it may have potential in treating conditions such as:

Research and Development[edit | edit source]

The development of synthetic cannabinoids like 5'-DMH-CBD is driven by the need to understand the structure-activity relationships of cannabinoids and to develop compounds with improved therapeutic profiles. Researchers are particularly interested in the potential of 5'-DMH-CBD to provide the therapeutic benefits of CBD with enhanced potency and efficacy.

Safety and Legal Status[edit | edit source]

As a synthetic cannabinoid, the safety profile of 5'-DMH-CBD is not as well-established as that of naturally occurring CBD. It is important for ongoing research to evaluate its toxicology, pharmacokinetics, and potential side effects. The legal status of 5'-DMH-CBD varies by jurisdiction, and it may be subject to regulation under laws governing synthetic cannabinoids.

Also see[edit | edit source]


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Contributors: Prab R. Tumpati, MD