16α-Fluoroestradiol

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16α-Fluoroestradiol is a synthetic, steroidal estrogen with high affinity for the estrogen receptor. It is a fluorinated derivative of estradiol, and was first described in the literature in 1966.

Chemistry[edit | edit source]

16α-Fluoroestradiol, also known as 16α-fluoro-17β-estradiol, is a synthetic estrane steroid and a derivative of estradiol. It is specifically a derivative of estradiol with a fluorine atom at the C16α position.

Pharmacology[edit | edit source]

16α-Fluoroestradiol has been found to possess high affinity for the estrogen receptor, about 14% of that of estradiol. It has been used in scientific research to study the estrogen receptor and the actions of estrogens.

See also[edit | edit source]

References[edit | edit source]

16α-Fluoroestradiol Resources
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Contributors: Prab R. Tumpati, MD