4-AcO-MET

4-AcO-MET (also known as 4-Acetoxy-N-methyl-N-ethyltryptamine) is a novel psychedelic substance of the tryptamine class. It is chemically similar to psilocybin, a naturally occurring psychedelic compound found in magic mushrooms.

Chemistry

4-AcO-MET belongs to the tryptamine class of psychedelic drugs. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-AcO-MET is substituted at R4 of its indole heterocycle with an acetoxy (AcO) functional group CH3COO−. It also contains a methyl group and an ethyl chain bound to the terminal amine RN of its tryptamine backbone (MET).

Pharmacology

The pharmacology of 4-AcO-MET is not well-studied. However, like other psychedelics, it is thought to act primarily by binding to serotonin receptors in the brain, particularly the 5-HT2A receptor. The compound's psychoactive effects are believed to come from its efficacy at the 5-HT2A receptors distributed throughout the brain.

Effects

The effects of 4-AcO-MET are often compared to those of psilocybin mushrooms, though with a shorter duration. Users report a wide range of effects, including visual hallucinations, enhanced colors, altered thinking processes, euphoria, and spiritual experiences. As with all psychedelics, the effects can vary greatly depending on the individual, the dosage, and the set and setting.

Risks

As with any psychedelic substance, using 4-AcO-MET carries risks. These can include psychological distress, panic attacks, and rare instances of psychosis. It is also possible that 4-AcO-MET could have harmful physical effects, though these are not well-documented due to the lack of scientific research on this substance.

Legal Status

The legal status of 4-AcO-MET varies by country. In some countries, it is a controlled substance, while in others it is legal to possess and use.

See Also

• Tryptamine
• Psychedelic substance
• Psilocybin