Estrogen patch
(Redirected from Estradot)
An estrogen patch or oestrogen patch is a transdermal delivery system for estradiol, primarily utilized as hormone replacement therapy (HRT) for the management of menopausal symptoms. It offers a distinct method of administration when compared to oral hormone replacement treatments.
Overview[edit | edit source]
The estrogen patch releases estradiol, the primary female sex hormone, directly into the bloodstream through the skin. This method of delivery is chosen to alleviate a range of symptoms associated with menopause and to prevent osteoporosis. While it shares many of the benefits and risks of conventional oral estrogen-only HRT, there are notable differences due to its transdermal administration.
Indications[edit | edit source]
The primary reasons for prescribing an estrogen patch include:
- Menopausal Symptoms:
- Hot flashes
- Vaginal dryness
- Mood swings
- Osteoporosis Prevention: By enhancing bone density.
Advantages Over Oral Estrogens[edit | edit source]
- Bypasses the Liver: Transdermal estrogen doesn't undergo first-pass metabolism in the liver, reducing liver-related side effects.
- Cholesterol and Triglycerides: Has a differential impact on cholesterol and triglycerides compared to oral estrogens.
- Reduced Risk of Venous Thromboembolism: Transdermal 17-beta estradiol doesn't have the increased risk of clot formation associated with oral ethinyl estradiol.
Potential Adverse Effects[edit | edit source]
As with any medication, estrogen patches have potential side effects:
- Skin irritation at the application site
- Breast tenderness
- Nausea
- Headache
- Fluid retention
However, some adverse effects associated with oral estrogen, especially those related to liver function, may be reduced or absent with the transdermal patch.
Administration[edit | edit source]
- The patch is typically applied to the lower abdomen or buttocks and should be changed once or twice weekly.
- It's essential to avoid applying creams or lotions to the application area as these may interfere with the absorption of estrogen.
- Users should rotate the patch's application site to reduce skin irritation risk.
Conclusion[edit | edit source]
The estrogen patch offers a viable alternative to oral HRT for women seeking relief from menopausal symptoms or osteoporosis prevention. The unique benefits of transdermal administration, including bypassing liver metabolism, make it a preferred choice for specific populations. However, patient-specific considerations should be taken into account when deciding on any form of HRT.
See Also[edit | edit source]
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