AM-3102

A synthetic cannabinoid

AM-3102 is a synthetic cannabinoid that acts as a potent agonist of the cannabinoid receptors. It is a member of the indole-3-carboxamide family of synthetic cannabinoids, which are often used in scientific research to study the endocannabinoid system.

Chemical Structure and Properties

AM-3102 is chemically classified as a synthetic cannabinoid, specifically an indole-3-carboxamide. Its IUPAC name is (1-(5-fluoropentyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone. The compound features a fluorinated pentyl chain, which is a common modification in synthetic cannabinoids to enhance potency and receptor affinity.

The molecular formula of AM-3102 is C₂₃H₃₀FNO, and it has a molecular weight of approximately 355.49 g/mol. The presence of the fluorine atom in the pentyl chain is significant as it can influence the lipophilicity and metabolic stability of the compound.

Pharmacology

AM-3102 acts as a full agonist at the CB₁ receptor and CB₂ receptor, which are part of the endocannabinoid system. This system is involved in a variety of physiological processes including pain sensation, mood regulation, and appetite control.

The binding affinity of AM-3102 for the CB₁ receptor is high, which suggests that it can produce significant psychoactive effects similar to those of tetrahydrocannabinol (THC), the primary psychoactive component of Cannabis. However, the exact effects and potency can vary significantly due to the synthetic nature of the compound.

Legal Status

The legal status of AM-3102 varies by country. In many jurisdictions, synthetic cannabinoids are controlled substances due to their potential for abuse and lack of medical use. Researchers must often obtain special licenses to work with these compounds.

Research Applications

AM-3102 is primarily used in scientific research to study the endocannabinoid system and the effects of cannabinoid receptor activation. It can help in understanding the role of these receptors in various physiological and pathological processes.

Safety and Toxicology

As with many synthetic cannabinoids, the safety profile of AM-3102 is not well-established. These compounds can have unpredictable effects and may pose significant health risks. Research is ongoing to better understand the toxicological implications of synthetic cannabinoid use.

Also see

• Synthetic cannabinoids
• Cannabinoid receptor
• Endocannabinoid system
• Tetrahydrocannabinol