JWH-042
Synthetic cannabinoid
| Drug Information | |||
|---|---|---|---|
| Image | 200 | ||
| Identifiers
ATC Code DrugBank
|
Chemical Data
Molecular Weight | ||
JWH-042 is a synthetic cannabinoid that acts as a potent agonist at both the CB1 and CB2 receptors. It is part of the naphthoylindole family of synthetic cannabinoids, which were originally developed for research purposes to study the endocannabinoid system.
Chemical Structure and Properties[edit | edit source]
JWH-042 is chemically classified as a naphthoylindole, which is a subclass of synthetic cannabinoids. The compound's full chemical name is (6aR,10aR)-3-(1-naphthalenylcarbonyl)-1,2,3,6,6a,7,10,10a-octahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran. It has a molecular formula of C24H26O2 and a molecular weight of 346.47 g/mol.
Pharmacology[edit | edit source]
JWH-042 acts as a full agonist at the CB1 and CB2 receptors, with a higher affinity for the CB2 receptor. This receptor selectivity is of interest in research as it may lead to the development of compounds with therapeutic potential that have fewer psychoactive effects compared to those that primarily target the CB1 receptor.
Legal Status[edit | edit source]
The legal status of JWH-042 varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of accepted medical use. It is important for researchers to be aware of the legal restrictions in their country when working with synthetic cannabinoids.
Research and Applications[edit | edit source]
JWH-042, like other synthetic cannabinoids, is used in scientific research to better understand the endocannabinoid system and its role in various physiological processes. Studies involving JWH-042 can provide insights into the development of new therapeutic agents for conditions such as chronic pain, inflammation, and neurodegenerative diseases.
Safety and Toxicology[edit | edit source]
The safety profile of JWH-042 has not been extensively studied in humans. However, synthetic cannabinoids in general have been associated with a range of adverse effects, including cardiovascular, neurological, and psychiatric symptoms. Researchers should exercise caution and adhere to safety protocols when handling these compounds.
Also see[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
