Polysporin

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Polysporin[edit | edit source]

Polysporin is a topical antibiotic ointment used to prevent infections in minor cuts, scrapes, and burns. It is a combination of two antibiotics: bacitracin and polymyxin B. Polysporin is known for its effectiveness in reducing the risk of infection and promoting healing in minor skin injuries.

Composition[edit | edit source]

Polysporin contains two active ingredients:

  • Bacitracin: A polypeptide antibiotic that works by inhibiting bacterial cell wall synthesis, leading to the death of the bacteria. It is effective against a range of gram-positive bacteria.
  • Polymyxin B: An antibiotic that targets gram-negative bacteria by disrupting the bacterial cell membrane, causing cell death.

These two antibiotics work synergistically to provide broad-spectrum antibacterial coverage.

Mechanism of Action[edit | edit source]

Polysporin acts by targeting the bacterial cell wall and membrane, which are essential for bacterial survival. Bacitracin interferes with the synthesis of the bacterial cell wall, while polymyxin B disrupts the integrity of the bacterial cell membrane. This dual action makes Polysporin effective against a variety of bacteria that can infect minor wounds.

Indications[edit | edit source]

Polysporin is indicated for:

  • Prevention of infection in minor cuts, scrapes, and burns.
  • Treatment of superficial skin infections caused by susceptible bacteria.

Usage[edit | edit source]

Polysporin should be applied to the affected area 1 to 3 times daily, as needed. The area should be cleaned before application, and a small amount of ointment should be applied. It can be covered with a sterile bandage if desired.

Side Effects[edit | edit source]

While Polysporin is generally well-tolerated, some individuals may experience:

  • Local irritation or allergic reactions.
  • Rash or itching at the site of application.

If severe allergic reactions occur, such as difficulty breathing or swelling, medical attention should be sought immediately.

Contraindications[edit | edit source]

Polysporin should not be used in individuals with known hypersensitivity to bacitracin, polymyxin B, or any other components of the ointment. It is also not recommended for use in deep or puncture wounds, animal bites, or serious burns without medical supervision.

Also see[edit | edit source]


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