Cannabinol-C2

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Detailed article on Cannabinol-C2


Synonyms
Cannabinol-C2
Drug Information
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Identifiers

CAS Number ATC Code PubChem DrugBank ChemSpider ID UNII KEGG ChEBI ChEMBL IUPAC Name

Chemical Data


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Molecular Weight



Cannabinol-C2 (CBN-C2) is a synthetic cannabinoid derivative that is structurally related to cannabinol (CBN), a naturally occurring compound found in the Cannabis plant. CBN-C2 is of interest in the field of pharmacology and medicinal chemistry due to its potential therapeutic properties and its role in the endocannabinoid system.

Chemical Structure and Properties[edit | edit source]

Cannabinol-C2 is a modified form of cannabinol, where specific alterations have been made to the chemical structure to enhance its pharmacological activity. The chemical structure of CBN-C2 includes a core tricyclic ring system typical of cannabinoids, with additional functional groups that may influence its interaction with cannabinoid receptors.

Pharmacology[edit | edit source]

CBN-C2 interacts with the cannabinoid receptors in the human body, primarily the CB1 receptor and the CB2 receptor. These receptors are part of the endocannabinoid system, which plays a crucial role in regulating various physiological processes such as pain, mood, appetite, and immune response.

Mechanism of Action[edit | edit source]

The mechanism of action of CBN-C2 involves binding to the CB1 and CB2 receptors, which are G-protein coupled receptors. This binding can lead to the modulation of neurotransmitter release, resulting in various physiological effects. CBN-C2 may exhibit partial agonist or antagonist activity at these receptors, depending on its specific chemical modifications.

Therapeutic Potential[edit | edit source]

Research into CBN-C2 is ongoing, with studies exploring its potential use in treating conditions such as chronic pain, inflammation, and neurodegenerative diseases. Its ability to modulate the endocannabinoid system makes it a candidate for further investigation in the context of cannabinoid-based therapies.

Synthesis[edit | edit source]

The synthesis of Cannabinol-C2 involves chemical modification of the natural cannabinol compound. This process typically includes steps such as selective functionalization and cyclization to achieve the desired structural changes. The synthetic route may vary depending on the specific properties targeted in the derivative.

Safety and Regulation[edit | edit source]

As a synthetic cannabinoid, CBN-C2 is subject to regulatory scrutiny. Its legal status may vary by jurisdiction, and it is important for researchers and clinicians to be aware of the regulatory framework governing its use in research and potential therapeutic applications.

Research and Development[edit | edit source]

Ongoing research is focused on understanding the pharmacokinetics, pharmacodynamics, and safety profile of CBN-C2. Clinical trials may be necessary to fully elucidate its therapeutic potential and to ensure its safety for human use.

Also see[edit | edit source]



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Contributors: Prab R. Tumpati, MD