Mixed amphetamine salts

Mixed Amphetamine Salts (MAS) are a combination of dextroamphetamine and levoamphetamine, two enantiomers of the psychoactive compound amphetamine. This combination is used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy. It is marketed under several brand names, including Adderall and Mydayis.

Pharmacology

The two enantiomers of amphetamine present in MAS have different pharmacological profiles. Dextroamphetamine is more potent and acts primarily on the central nervous system, while levoamphetamine has a greater effect on the peripheral nervous system. Together, they increase the levels of dopamine and norepinephrine in the brain, enhancing focus, attention, and alertness.

Medical Uses

MAS is primarily used in the treatment of ADHD, a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity. It is also used in the treatment of narcolepsy, a sleep disorder that causes excessive daytime sleepiness and sudden attacks of sleep.

Side Effects

Common side effects of MAS include insomnia, decreased appetite, and dry mouth. More serious side effects can include increased heart rate, high blood pressure, and psychological effects such as anxiety and paranoia.

Legal Status

In many countries, including the United States, MAS is classified as a Schedule II controlled substance, indicating a high potential for abuse and dependence.

See Also

• Amphetamine
• Dextroamphetamine
• Levoamphetamine
• Attention Deficit Hyperactivity Disorder
• Narcolepsy

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