Aseptic necrosis

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Aseptic necrosis (ay-SEP-tik neh-KROH-sis) is a condition in which there is a loss of blood flow to bone tissue, which causes the bone to die.

Common bones affected[edit | edit source]

It is most common in the hips, knees, shoulders, and ankles.

Steroid use and aseptic necrosis[edit | edit source]

It may be caused by long-term use of steroids, alcohol abuse, diving underwater, joint injuries, and certain diseases, such as cancer and arthritis.

Medication induced aseptic necrosis[edit | edit source]

It may also occur at some point in time after cancer treatment that included methotrexate, bisphosphonates, or corticosteroids as noted above.

Other names[edit | edit source]

Also called avascular necrosis, ischemic necrosis, and osteonecrosis.

Aseptic necrosis Resources
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Contributors: Prab R. Tumpati, MD