Anticholinergic agents
Anticholinergic Agents are a group of drugs that block the action of the neurotransmitter acetylcholine in the brain. These agents are used to treat a variety of medical conditions, including gastrointestinal disorders, respiratory diseases, and certain neurological disorders.
Mechanism of Action[edit | edit source]
Anticholinergic agents work by blocking the action of acetylcholine at muscarinic receptors in the brain and peripheral tissues. This results in a reduction in the activity of the parasympathetic nervous system, which is responsible for rest and digest functions.
Uses[edit | edit source]
Anticholinergic agents are used in the treatment of a variety of conditions. These include:
- Gastrointestinal disorders: These agents can reduce the activity of the gastrointestinal tract, helping to alleviate symptoms of conditions such as irritable bowel syndrome and peptic ulcer disease.
- Respiratory diseases: Anticholinergic agents can help to relax the muscles in the airways, making them useful in the treatment of conditions such as chronic obstructive pulmonary disease and asthma.
- Neurological disorders: Certain anticholinergic agents can be used to treat conditions such as Parkinson's disease and epilepsy.
Side Effects[edit | edit source]
Like all drugs, anticholinergic agents can have side effects. These can include dry mouth, blurred vision, constipation, and confusion. In older adults, long-term use of these agents has been associated with an increased risk of dementia.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD