Ionsys
Transdermal system for pain management
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Ionsys is a transdermal system used for the management of acute pain in a hospital setting. It is designed to deliver the opioid fentanyl through the skin using an iontophoretic mechanism. This system allows for patient-controlled analgesia, providing a non-invasive method for pain relief.
Mechanism of Action[edit | edit source]
Ionsys utilizes an iontophoretic delivery system, which employs a small electric current to drive the fentanyl through the skin and into the bloodstream. This method allows for rapid onset of pain relief and precise control over the dosage administered.
Indications[edit | edit source]
Ionsys is indicated for the short-term management of acute postoperative pain in adult patients who require opioid analgesia in a hospital setting. It is typically used in patients who are able to self-administer the medication and are under close medical supervision.
Contraindications[edit | edit source]
Ionsys should not be used in patients with known hypersensitivity to fentanyl or any components of the system. It is also contraindicated in patients with severe respiratory depression, acute or severe bronchial asthma, and gastrointestinal obstruction.
Side Effects[edit | edit source]
Common side effects of Ionsys include:
Serious side effects may include respiratory depression, severe hypotension, and anaphylaxis.
Administration[edit | edit source]
Ionsys is applied to the skin, typically on the upper outer arm or chest. The system is activated by the patient pressing a button, which delivers a pre-set dose of fentanyl. The device is designed to deliver up to 80 doses over a 24-hour period.
Monitoring[edit | edit source]
Patients using Ionsys should be closely monitored for signs of respiratory depression, especially within the first 24-72 hours of initiating therapy. Regular assessment of pain relief and side effects is essential to ensure safe and effective use.
Related Pages[edit | edit source]
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