List of chemotherapeutic agents
(Redirected from List of antineoplastic agents)
Chemotherapeutic agents are a class of drugs used primarily for treating cancer by killing or inhibiting the growth of cancer cells. These agents encompass a broad range of medications with diverse mechanisms of action and specificity towards cancerous cells. This article provides an overview of chemotherapeutic agents, their classification, mechanisms, applications in cancer treatment, and associated side effects.
Introduction[edit | edit source]
Chemotherapy involves the use of chemical substances, known as chemotherapeutic agents, to treat disease. In the context of cancer, chemotherapy represents a cornerstone of treatment, either as a standalone therapy or in combination with surgery, radiation therapy, and other forms of cancer treatment. The goal of chemotherapy can vary from curative intent to palliation, depending on the cancer type, stage, and overall health of the patient.
Classification of Chemotherapeutic Agents[edit | edit source]
Chemotherapeutic agents are classified based on their chemical structure, mechanism of action, and origin. Major classes include:
Alkylating Agents[edit | edit source]
These compounds work by adding alkyl groups to DNA, leading to DNA damage and preventing cancer cells from dividing. Examples include cyclophosphamide and ifosfamide.
Antimetabolites[edit | edit source]
Mimicking the substrates of metabolic pathways, antimetabolites interfere with DNA and RNA synthesis. Methotrexate and 5-fluorouracil are common examples.
Natural Products[edit | edit source]
Derived from plants, microorganisms, and marine species, these agents include vinca alkaloids (e.g., vincristine), taxanes (e.g., paclitaxel), and anthracyclines (e.g., doxorubicin).
Topoisomerase Inhibitors[edit | edit source]
These agents interfere with the topoisomerases, enzymes that help unwind DNA during replication, leading to DNA damage. Examples are etoposide and irinotecan.
Antitumor Antibiotics[edit | edit source]
Despite the name, these agents are not used for treating infections but for their ability to bind to DNA and inhibit RNA synthesis. Dactinomycin and bleomycin fall into this category.
Targeted Therapies[edit | edit source]
A newer class of drugs that specifically target molecular differences between cancer and normal cells. Examples include imatinib (a tyrosine kinase inhibitor) and trastuzumab (a monoclonal antibody).
Mechanisms of Action[edit | edit source]
The mechanisms of action of chemotherapeutic agents vary widely but generally involve the disruption of cellular processes critical for cancer cell growth and division. These mechanisms include DNA damage, inhibition of DNA or RNA synthesis, disruption of mitotic spindles, and inhibition of specific enzymes or growth factors.
Uses in Cancer Treatment[edit | edit source]
Chemotherapeutic agents are used in various settings across the cancer treatment continuum, including:
Curative Therapy[edit | edit source]
Aimed at curing the cancer, often used in early-stage cancers or specific types of cancer that are highly responsive to chemotherapy.
Adjuvant Therapy[edit | edit source]
Administered after primary treatment (such as surgery) to eliminate any remaining cancer cells and reduce the risk of cancer recurrence.
Neoadjuvant Therapy[edit | edit source]
Given before primary treatment to shrink tumors, making them easier to remove surgically.
Palliative Care[edit | edit source]
Used to relieve symptoms and improve the quality of life in patients with advanced cancer.
Side Effects[edit | edit source]
The side effects of chemotherapy are a consequence of the damage to rapidly dividing cells, including healthy cells. Common side effects include nausea and vomiting, hair loss, fatigue, increased risk of infections, and myelosuppression. The severity and type of side effects vary depending on the specific agents used, the dosage, and the individual patient's response.
Comprehensive list of chemotherapeutic agents[edit | edit source]
- 1,4,6-Androstatriene-3,17-dione
- 17α-Ethynyl-3α-androstanediol
- 2-Methoxyestradiol
- 2-Methoxyestradiol disulfamate
- 20α-Dihydroprogesterone
- 3,3'-Diindolylmethane
- 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone
- 4'-Hydroxynorendoxifen
- 4-Aminosalicylic acid
- 4-Androstene-3,6,17-trione
- 4-Deoxypyridoxine
- 4-Hydroxycyclophosphamide
- 4-Hydroxytestosterone
- 5N-Bicalutamide
- 5α-Dihydronorethisterone
- 6-Diazo-5-oxo-L-norleucine
- 7+3 (chemotherapy)
- 8-Azaguanine
- ABT-510
- ABTL0812
- ABVD
- ADE (chemotherapy)
- ADH-1
- AI-10-49
- ALK inhibitor
- AM-251 (drug)
- AMG 319
- AOH1996
- ATC code L01
- Abagovomab
- Abdullahi v. Pfizer, Inc.
- Abexinostat
- Abiraterone acetate
- Abituzumab
- Abrocitinib
- Acacetin
- Acadesine
- Acalabrutinib
- Acefluranol
- Aceglatone
- Aclarubicin
- Acolbifene
- Acridine carboxamide
- Actinium-225
- Acutissimin A
- Adagrasib
- Adavosertib
- Adecatumumab
- Adegramotide
- Aderbasib
- Adjuvant therapy
- Adozelesin
- Afatinib
- Afimoxifene
- Aflibercept
- Alacizumab pegol
- Alanosine
- Alatrofloxacin
- Aldoxorubicin
- Alectinib
- Alemtuzumab
- Alestramustine
- Alitretinoin
- Alkyl-lysophospholipids
- Alkylating antineoplastic agent
- Allovectin-7
- Allylestrenol
- Alternating electric field therapy
- Altretamine
- Alvocidib
- Amarogentin
- Amatuximab
- Amifloxacin
- Amifostine
- Amikhelline
- Aminoglutethimide
- Aminolevulinic acid
- Aminopterin
- Amivantamab
- Amonafide
- Amphinex
- Amrubicin
- Amsacrine
- Anabolic steroid
- Anagrelide
- Anastrozole
- Anatumomab mafenatox
- Androgen receptor degrader
- Androstenediol diacetate
- Anecortave acetate
- Angiogenesis inhibitor
- Angiokinase inhibitors
- Angiostatin
- Angiozyme
- Annamycin
- Anthracycline
- Anthramycin
- Anti-CD22 immunotoxin
- Antiandrogen
- Antibody–drug conjugate
- Anticarcinogen
- Antiestrogen
- Antifolate
- Antimetabolite
- Apalutamide
- Apatinib
- Apaziquone
- Aphidicolin
- Apigenin
- Arabinopyranosyl-N-methyl-N-nitrosourea
- Aromatase inhibitor
- Arsenic trioxide
- Artemisinin
- Asciminib
- Ascrinvacumab
- Asparaginase
- Asunercept
- Atamestane
- Atezolizumab
- Atiprimod
- Atrasentan
- Atrimustine
- Autogene cevumeran
- Avapritinib
- Avelumab
- Axicabtagene ciloleucel
- Axitinib
- Azacitidine
- Azaserine
- Azathioprine
- BEACOPP
- BI 811283
- BMS-641988
- BOLD-100
- Bafetinib
- Baicalein
- Balofloxacin
- Baricitinib
- Bavituximab
- Bazedoxifene
- Bcr-Abl tyrosine-kinase inhibitor
- Bectumomab
- Belantamab mafodotin
- Beloranib
- Belotecan
- Bemcentinib
- Bempegaldesleukin
- Bendamustine
- Benzilylcholine mustard
- Berberine
- Bergapten
- Besifloxacin
- Bevacizumab
- Bexarotene
- Bicalutamide
- Bifonazole
- Biochanin A
- Bioclipse
- Biosynthesis of doxorubicin
- Birabresib
- Biricodar
- Bis(2-chloroethyl)sulfide
- Bivatuzumab mertansine
- Bleomycin
- Blinatumomab
- Blister agent
- Bohemic acid
- Bortezomib
- Bosutinib
- Breast cancer chemotherapy
- Brentuximab vedotin
- Brigatinib
- Brilanestrant
- Brivanib alaninate
- Bromoketoprogesterone
- Bropirimine
- Brostallicin
- Bryostatin
- Buparlisib
- Buserelin
- Busulfan
- Buthionine sulfoximine
- C-1027
- CAPOX
- CBR96-doxorubicin immunoconjugate
- CBV (chemotherapy)
- CEPP
- CHOP (chemotherapy)
- CMF (chemotherapy)
- COPP (chemotherapy)
- CP-944629
- CRLX101
- CYP17A1 inhibitor
- Cabazitaxel
- Cabozantinib
- Cadonilimab
- Calaspargase pegol
- Camidanlumab tesirine
- Camptothecin
- Canakinumab
- Cancer Drugs Fund
- Cancer immunotherapy
- Canertinib
- Cantharidin
- Cantuzumab mertansine
- Cantuzumab ravtansine
- Capecitabine
- Capmatinib
- Carboplatin
- Carboquone
- Carboxycyclophosphamide
- Carfilzomib
- Carmofur
- Carmustine
- Cartilage-derived angiogenesis inhibitor
- Carubicin
- Catumaxomab
- Cediranib
- Celecoxib
- Cemiplimab
- Cerdulatinib
- Ceritinib
- Cetuximab
- Chemically linked Fab
- Chemoimmunotherapy
- Chemoprotective agent
- Chemosensitivity assay
- Chemosensitizer
- Chemotherapy
- Chemotherapy regimen
- Chemotherapy-induced nausea and vomiting
- Chlorambucil
- Chlormadinone acetate
- Chlormethine
- Chlornaltrexamine
- Chlornaphazine
- Chloroethylclonidine
- Chlorotoxin
- Chlorotrianisene
- Chloroxymorphamine
- Chlorozotocin
- Chrysin
- Cilengitide
- Ciltacabtagene autoleucel
- Ciprofloxacin
- Cirmtuzumab
- Cisplatin
- Citatuzumab bogatox
- Cixutumumab
- Cladribine
- Clevegen
- Clinafloxacin
- Clofarabine
- Clostridium novyi-NT
- Clotrimazole
- Cobimetinib
- Cofetuzumab pelidotin
- Combretastatin A-4
- Conbercept
- Conjugated estrogens
- Conjugated linoleic acid
- Copanlisib
- Cortifen
- Cosmomycin B
- Coumestrol
- Crenolanib
- Crimidine
- Crizotinib
- Cryptolepine
- Custirsen
- Cyclophosphamide
- Cyproterone acetate
- Cytarabine
- Cytestrol acetate
- Cytoskeletal drugs
- DAT (chemotherapy)
- DHA-paclitaxel
- DHAP (chemotherapy)
- DSP-4
- DT-PACE
- Dabrafenib
- Dacarbazine
- Dacetuzumab
- Dacomitinib
- Dactinomycin
- Dactolisib
- Damnacanthal
- Danofloxacin
- Daratumumab
- Darinaparsin
- Darolutamide
- Dasatinib
- Daunorubicin
- Daunorubicin/cytarabine
- Decitabine
- Delafloxacin
- Delgocitinib
- Demcizumab
- Denifanstat
- Denileukin diftitox
- Denintuzumab mafodotin
- Depatuxizumab mafodotin
- Detumomab
- Deucravacitinib
- Deuruxolitinib
- Devimistat
- Dexrazoxane
- Dibrospidium chloride
- Dibutylchloromethyltin chloride
- Dichloroacetic acid
- Dicycloplatin
- Diethylstilbestrol
- Diethylstilbestrol disulfate
- Differentiation therapy
- Diflomotecan
- Difloxacin
- Dihydrofluoxymesterone
- Dimethyl(trifluoromethylthio)arsine
- Dinaciclib
- Discodermolide
- Docetaxel
- Dose-dense chemotherapy
- Dostarlimab
- Doxifluridine
- Doxorubicin
- Droloxifene
- Dronabinol
- Drostanolone propionate
- Duligotuzumab
- Duocarmycin
- Durvalumab
- Dusigitumab
- Dutasteride
- Duvelisib
- Dz13
- EM-5854
- EPI-7386
- EPOCH (chemotherapy)
- ERX-11
- ESHAP
- Econazole
- Edrecolomab
- Efaproxiral
- Eftilagimod alpha
- Eganelisib
- Elacestrant
- Electrochemotherapy
- Elesclomol
- Ellagitannin
- Ellipticine
- Elotuzumab
- Elranatamab
- Elsamitrucin
- Enasidenib
- Encorafenib
- Endostatin
- Endosulfan
- Endoxifen
- Enfortumab vedotin
- Enilconazole
- Enloplatin
- Enobosarm
- Enocitabine
- Enoticumab
- Enoxacin
- Enrofloxacin
- Ensituximab
- Entolimod
- Entospletinib
- Entrectinib
- Enzalutamide
- Epacadostat
- Epcoritamab
- Epigallocatechin gallate
- Epirubicin
- Epitiostanol
- Epothilone
- Epoxomicin
- Epratuzumab
- Erbulozole
- Erdafitinib
- Eribulin
- Erlotinib
- Ertumaxomab
- Esterified estrogens
- Estetrol (medication)
- Estradiol (medication)
- Estradiol benzoate
- Estradiol dipropionate
- Estradiol mustard
- Estradiol undecylate
- Estradiol valerate
- Estramustine
- Estramustine phosphate
- Estrogen (medication)
- Estromustine
- Etacstil
- Etaracizumab
- Ethamoxytriphetol
- Ethandrostate
- Ethidium bromide
- Ethinylestradiol
- Ethinylestradiol sulfonate
- Ethionine
- Ethylcholine mustard
- Ethyldichloroarsine
- Etirinotecan pegol
- Etoglucid
- Etoposide
- Everolimus
- Evofosfamide
- Exatecan
- Exemestane
- Exisulind
- FCM (chemotherapy)
- FLAG (chemotherapy)
- FM (chemotherapy)
- FOLFIRI
- FOLFIRINOX
- FOLFOX
- FOLFOXIRI
- Fadrozole
- Famitinib
- Faricimab
- Fenarimol
- Fenretinide
- Figitumumab
- Filanesib
- Filgotinib
- Finafloxacin
- Finrozole
- Fisetin
- Fleroxacin
- Floxuridine
- Fluasterone
- Fludarabine
- Flumequine
- Fluoromedroxyprogesterone acetate
- Fluorometholone acetate
- Fluorouracil
- Fluoxymesterone
- Flutamide
- Folinic acid
- Foretinib
- Formestane
- Forodesine
- Fosbretabulin
- Fosfestrol
- Fostamatinib
- Fotemustine
- Fruquintinib
- Fulvestrant
- Futibatinib
- Futuximab
- GTx-758
- GVAX
- GVD (chemotherapy)
- Galunisertib
- Gandotinib
- Gatifloxacin
- Gavilimomab
- Gedatolisib
- Gedunin
- Gefitinib
- GemOx
- Gemcitabine
- Gemifloxacin
- Gemtuzumab ozogamicin
- Gestonorone caproate
- Gilteritinib
- Gilvocarcin V
- Ginkgotoxin
- Glasdegib
- Glembatumumab vedotin
- Glesatinib
- Globo H
- Glofitamab
- Glucarpidase
- Glufosfamide
- Gold nanoparticles in chemotherapy
- Gonadotropin-releasing hormone agonist
- Gonadotropin-releasing hormone modulator
- Gossypetin
- Grandinin
- Grepafloxacin
- Growth factor receptor inhibitor
- HAMLET (protein complex)
- HN1 (nitrogen mustard)
- HN3 (nitrogen mustard)
- HS-10365
- HU-336
- HU-345
- Hepatic arterial infusion
- Hesperetin
- High-dose estrogen therapy
- Histone deacetylase inhibitor
- History of cancer chemotherapy
- Hormonal therapy (oncology)
- Hydroxycarbamide
- Hyper-CVAD
- Hyperthermic intrathoracic chemotherapy
- Hypomethylating agent
- ICE (chemotherapy)
- ICI-164384
- ICI-85966
- ICRF 193
- IFL (chemotherapy)
- IMEP (chemotherapy)
- IMM-101
- IRGD
- Ibafloxacin
- Iberdomide
- Ibritumomab tiuxetan
- Ibrutinib
- Ice chips
- Icotinib
- Icrucumab
- Idarubicin
- Idelalisib
- Idoxifene
- Ieramilimab
- Ifinatamab deruxtecan
- Ifosfamide
- Imalumab
- Imatinib
- Imetelstat
- Imexon
- Imgatuzumab
- Imiquimod
- Imlunestrant
- Immunoconjugate
- Inavolisib
- Indatuximab ravtansine
- Indisulam
- Indium (111In) altumomab pentetate
- Indium (111In) capromab pendetide
- Indium (111In) igovomab
- Indium (111In) satumomab pendetide
- Indolocarbazole
- Induction chemotherapy
- Inebilizumab
- Infigratinib
- Ingenol mebutate
- Inotuzumab ozogamicin
- Intetumumab
- Iodine (131 I) derlotuximab biotin
- Ipatasertib
- Ipilimumab
- Iratumumab
- Irinotecan
- Irofulven
- Irosustat
- Isatuximab
- Isoconazole
- Isoniazid
- Istiratumab
- Ivarmacitinib
- Ivosidenib
- Ixabepilone
- Ixazomib
- JNJ-Q2
- JT-010
- Jaktinib
- Janus kinase 3 inhibitor
- Janus kinase inhibitor
- KB-16
- KP1019
- Kairbaan Hodivala-Dilke
- Kedarcidin
- Ketoconazole
- Ketodarolutamide
- LG-2527
- LS-1727
- Labetuzumab
- Laniquidar
- Lapatinib
- Larotaxel
- Larotrectinib
- Lascufloxacin
- Lasofoxifene
- Leflutrozole
- Lenalidomide
- Leniolisib
- Lestaurtinib
- Letrozole
- Leuprorelin
- Levofloxacin
- Lewisite
- Lewisite 2
- Lewisite 3
- Lexatumumab
- Liarozole
- Lifastuzumab vedotin
- Lilotomab
- Linifanib
- Linoleic acid
- Linolenic acid
- Linsitinib
- Lintuzumab
- Lipoplatin
- Liposomal daunorubicin
- Liquiritigenin
- Lirilumab
- Lisocabtagene maraleucel
- Lobaplatin
- Lomefloxacin
- Lomustine
- Loncastuximab tesirine
- Lonidamine
- Lorlatinib
- Lorvotuzumab mertansine
- Losoxantrone
- Low-dose chemotherapy
- Lucanthone
- Lucatumumab
- Lucitanib
- Luminespib
- Lurbinectedin
- Lurtotecan
- Lyngbyatoxin-a
- M2613
- MDX-1097
- MG132
- MINE (chemotherapy)
- MK-2206
- MK-2870
- MK-434
- MOPP (chemotherapy)
- MRTX1133
- MTOR inhibitors
- Mafosfamide
- Mannomustine
- Mannosulfan
- Mapatumumab
- Marbofloxacin
- Margetuximab
- Marimastat
- Masitinib
- Masoprocol
- Matuzumab
- Medicinal uses of fungi
- Medroxyprogesterone acetate
- Megestrol acetate
- Melanizing agents
- Melatonin
- Melengestrol
- Melengestrol acetate
- Melphalan
- Menogaril
- Mepitiostane
- Merafloxacin
- Mercaptopurine
- Merestinib
- Mertansine
- Mesna
- Metapristone
- Metastasis suppressor
- Methotrexate
- Methoxsalen
- Methyl aminolevulinate
- Methyldichloroarsine
- Methylepitiostanol
- Methyltestosterone
- Metronomic therapy
- Miconazole
- Milatuzumab
- Miltefosine
- Minamestane
- Minretumomab
- Miproxifene
- Miproxifene phosphate
- Miriplatin
- Mirvetuximab soravtansine
- Mitobronitol
- Mitoguazone
- Mitomycin C
- Mitomycins
- Mitosene
- Mitotane
- Mitotic inhibitor
- Mitoxantrone
- Mitumomab
- Modotuximab
- Momelotinib
- Monoclonal antibody therapy
- Monomethyl auristatin E
- Monomethyl auristatin F
- Monomethylhydrazine
- Mosunetuzumab
- Motesanib
- Moxetumomab pasudotox
- Moxifloxacin
- Mubritinib
- Mustard gas
- Myricetin
- N,N-Didesmethyltamoxifen
- N,N-Dimethyl-2-chloro-2-phenylethylamine
- N-Desmethylapalutamide
- N-Desmethylenzalutamide
- N-Desmethyltamoxifen
- N-Nitroso-N-methylurea
- NAMI-A
- NK012
- NL-201
- Nacolomab tafenatox
- Nadifloxacin
- Nafoxidine
- Nalidixic acid
- Naptumomab estafenatox
- Naringenin
- Navitoclax
- Necitumumab
- Nedaplatin
- Nelarabine
- Nemtabrutinib
- Neocarzinostatin
- Neoxaline
- Neratinib
- Nesvacumab
- Nilotinib
- Nilutamide
- Nimorazole
- Nimotuzumab
- Nimustine
- Nintedanib
- Nirogacestat
- Nitrogen mustard
- Nivolumab
- Nivolumab/relatlimab
- Nocodazole
- Nogalamycin
- Non steroidal aromatase inhibitors
- Nonsteroidal antiandrogen
- Norendoxifen
- Norethisterone
- Norfloxacin
- Normustine
- Novobiocin
- O-Mustard
- O6-Benzylguanine
- ONX-0801
- OSI-7904
- OSU-03012
- OX1001
- Obatoclax
- Obinutuzumab
- Oblimersen
- Oclacitinib
- Ofatumumab
- Ofloxacin
- Ofranergene obadenovec
- Olaratumab
- Olmutinib
- Oltipraz
- Olutasidenib
- Olverembatinib
- Ombrabulin
- Onapristone
- Ontuxizumab
- Opnurasib
- Oportuzumab monatox
- Oprozomib
- Orbifloxacin
- Oregovomab
- Ortataxel
- Osimertinib
- Oxaliplatin
- Oxofluoxymesterone
- Ozarelix
- Ozogamicin
- PAC-1
- PR-104
- Paclitaxel
- Paclitaxel trevatide
- Pacritinib
- Padeliporfin
- Palau'amine
- Palmitic acid
- Palytoxin
- Panitumumab
- Panomifene
- Parsatuzumab
- Patritumab
- Patritumab deruxtecan
- Pazopanib
- Pazufloxacin
- Pederin
- Peficitinib
- Pefloxacin
- Pegaptanib
- Pegaspargase
- Pegdinetanib
- Pelareorep
- Pembrolizumab
- Pemetrexed
- Pemigatinib
- Pemtumomab
- Pentostatin
- Perfosfamide
- Pertuzumab
- Pertuzumab/trastuzumab/hyaluronidase
- Pevonedistat
- Phenanthriplatin
- Phenestrol
- Phenoxybenzamine
- Phenyldichloroarsine
- Phenytoin
- Phosphoinositide 3-kinase inhibitor
- Phototrexate
- Picibanil
- Picoplatin
- Pimitespib
- Pinatuzumab vedotin
- Pingyangmycin
- Pinocembrin
- Pipendoxifene
- Pipobroman
- Pirarubicin
- Pirtobrutinib
- Pixantrone
- Platinum-based antineoplastic
- Plicamycin
- Plinabulin
- Plitidepsin
- Plomestane
- Polatuzumab vedotin
- Polmacoxib
- Polyestradiol phosphate
- Polymer-drug conjugates
- Ponatinib
- Ponsegromab
- Porfimer sodium
- Porfiromycin
- Poziotinib
- Pradofloxacin
- Pralatrexate
- Pralsetinib
- Prednimustine
- Prexasertib
- Prinomastat
- Pritumumab
- Procarbazine
- Prochloraz
- Prohibitin-targeting peptide 1
- Propiconazole
- Prostaglandin E2
- Proteasome inhibitor
- Protein-bound paclitaxel
- Proxalutamide
- Prulifloxacin
- Psoralen
- Purine analogue
- Pyrimidine analogue
- Quadrosilan
- Quercetin
- Quisinostat
- Quizartinib
- R-CHOP
- R-HDAC
- RAPTA
- RD-162
- RO4929097
- Radium-223
- Radotinib
- Radretumab
- Ralimetinib
- Raltitrexed
- Ramucirumab
- Ranibizumab
- Ranimustine
- Rasburicase
- Rebeccamycin
- Regorafenib
- Relatlimab
- Relugolix
- Remibrutinib
- Rencofilstat
- Repotrectinib
- Resimmune
- Resiquimod
- Resveratrol
- Retifanlimab
- Rezvilutamide
- Ribonucleotide reductase inhibitor
- Rigosertib
- Rindopepimut
- Ripretinib
- Ritlecitinib
- Rituximab
- Robatumumab
- Rociletinib
- Rogletimide
- Romidepsin
- Rotenone
- Rovalpituzumab tesirine
- Rubitecan
- Rufloxacin
- Ruthenium anti-cancer drugs
- Ruxolitinib
- SN-38
- Sabarubicin
- Sabizabulin
- Sacituzumab govitecan
- Sakuranetin
- Salinosporamide A
- Sapacitabine
- Sapanisertib
- Saracatinib
- Sarafloxacin
- Saridegib
- Satraplatin
- Savolitinib
- Selinexor
- Selpercatinib
- Selumetinib
- Selvigaltin
- Semaxanib
- Semustine
- Sequential high-dose chemotherapy
- Seribantumab
- Sesquimustard
- Seviteronel
- Sibrotuzumab
- Sidney Farber
- Signal transduction inhibitor
- Silver nanoparticle
- Sintilimab
- Sitafloxacin
- Sitravatinib
- Sivifene
- Sofituzumab vedotin
- Solitomab
- Sonidegib
- Sorafenib
- Sotorasib
- Sparfloxacin
- Sparsomycin
- Spindle poison
- Squalamine
- Src inhibitor
- Stanford V
- Steganacin
- Steroidal antiandrogen
- Steroidal aromatase inhibitor
- Streptozotocin
- Study of Tamoxifen and Raloxifene
- Sturamustine
- Sulforaphane
- Sunitinib
- Swainsonine
- T-2 mycotoxin
- T790M
- TAS-108
- TCH (chemotherapy)
- TL-301
- TNP-470
- Talaporfin
- Talazoparib
- Talimogene laherparepvec
- Talquetamab
- Tamibarotene
- Tamoxifen
- Tanespimycin
- Taplitumomab paptox
- Tarextumab
- Targeted therapy
- Tariquidar
- Tarlatamab
- Tasquinimod
- Taxane
- Taxoid
- Taxuspines
- Tazemetostat
- Tebentafusp
- Technetium (99mTc) arcitumomab
- Technetium (99mTc) fanolesomab
- Technetium (99mTc) nofetumomab merpentan
- Technetium (99mTc) pintumomab
- Technetium (99mTc) sulesomab
- Technetium (99mTc) votumumab
- Techtochrysin
- Teclistamab
- Tegafur
- Tegafur/gimeracil/oteracil
- Tegafur/uracil
- Temafloxacin
- Temoporfin
- Temozolomide
- Temsirolimus
- Teniposide
- Tepotinib
- Teprotumumab
- Terpestacin
- Tesetaxel
- Tesevatinib
- Tesmilifene
- Testifenon
- Testolactone
- Testosterone (medication)
- Tetrahydrocannabinol
- Thiotepa
- Thymidylate synthase inhibitor
- Tiazofurin
- Tigilanol tiglate
- Tilomisole
- Tioconazole
- Tioguanine
- Tirapazamine
- Tisagenlecleucel
- Tisotumab vedotin
- Tivantinib
- Tivozanib
- Toceranib
- Tofacitinib
- Topoisomerase inhibitor
- Topotecan
- Toremifene
- Toripalimab
- Tosufloxacin
- Tovetumab
- Toxopyrimidine
- Trabectedin
- Trastuzumab
- Trastuzumab deruxtecan
- Trastuzumab emtansine
- Trastuzumab/hyaluronidase
- Treosulfan
- Tretinoin
- Triadimefon
- Triaziquone
- Triciribine
- Triethylenemelamine
- Trifluridine
- Trifluridine/tipiracil
- Trilaciclib
- Trimethoprim
- Trimetrexate
- Triphenylchloroethylene
- Triphenylmethylethylene
- Triplatin tetranitrate
- Trofosfamide
- Troglitazone
- Tropoflavin
- Trovafloxacin
- Troxacitabine
- Tucatinib
- Tucotuzumab celmoleukin
- Tumstatin
- Tyrosine kinase inhibitor
- Ubenimex
- Upadacitinib
- Upamostat
- Uramustine
- Urelumab
- V600E
- VAMP regimen
- VEGFR-2 inhibitor
- Vadastuximab talirine
- Vadimezan
- Valproate
- Valrubicin
- Valspodar
- Vandetanib
- Vandortuzumab vedotin
- Vantictumab
- Vanucizumab
- Vapreotide
- Vatalanib
- Veliparib
- Vemurafenib
- Venetoclax
- Vepdegestrant
- Vernolepin
- Verteporfin
- Vinblastine
- Vinca alkaloid
- Vincristine
- Vindesine
- Vinflunine
- Vinorelbine
- Vintafolide
- Vismodegib
- Vitamin K antagonist
- Vitaxin
- Vocimagene amiretrorepvec/flucytosine
- Volasertib
- Volociximab
- Vorasidenib
- Vorinostat
- Vorozole
- Vorsetuzumab mafodotin
- Vosaroxin
- Vosilasarm
- Voxtalisib
- Whole brain radiotherapy
- XL-413
- Yellow Cross (chemical warfare)
- Yttrium (90Y) clivatuzumab tetraxetan
- Yttrium (90Y) tacatuzumab tetraxetan
- ZB716
- ZGN-1061
- Zabofloxacin
- Zalutumumab
- Zanzalintinib
- Zearalenone
- Zibotentan
- Zindoxifene
- Zolbetuximab
- Zoptarelin doxorubicin
- Zorubicin
- Zosuquidar
- Α-Amanitin
- Α-Naphthoflavone
- Β-Hydroxy β-methylbutyric acid
- Δ4-Abiraterone
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