Depakene

From WikiMD's Wellness Encyclopedia

Depakene[edit | edit source]

Depakene is a brand name for the medication valproic acid, which is used primarily to treat seizure disorders, bipolar disorder, and to prevent migraine headaches. It is an anticonvulsant and mood-stabilizing drug.

Medical Uses[edit | edit source]

Depakene is indicated for the treatment of various types of seizure disorders, including:

It is also used in the management of bipolar disorder, particularly for the treatment of manic episodes. Additionally, Depakene is prescribed for the prevention of migraine headaches.

Mechanism of Action[edit | edit source]

Valproic acid, the active ingredient in Depakene, works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter that helps to calm nerve activity, which can help to prevent seizures and stabilize mood.

Dosage and Administration[edit | edit source]

Depakene is available in oral forms, including capsules and syrup. The dosage of Depakene is individualized based on the patient's age, weight, and the condition being treated. It is important to follow the prescribing physician's instructions and not to adjust the dose without medical advice.

Side Effects[edit | edit source]

Common side effects of Depakene include:

Serious side effects may include:

Patients should be monitored for signs of liver dysfunction, especially during the first six months of treatment.

Contraindications[edit | edit source]

Depakene is contraindicated in patients with:

  • Known hypersensitivity to valproic acid
  • Significant liver disease
  • Urea cycle disorders

Interactions[edit | edit source]

Depakene can interact with other medications, including:

These interactions can affect the levels of valproic acid in the blood and may require dose adjustments.

Pregnancy and Lactation[edit | edit source]

Depakene is classified as a pregnancy category D medication, indicating there is evidence of risk to the fetus. It should be used during pregnancy only if the potential benefits justify the potential risks. Women of childbearing potential should use effective contraception while taking Depakene.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]

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Contributors: Prab R. Tumpati, MD