25B-NB4OMe

A synthetic psychedelic compound

25B-NB4OMe is a synthetic psychedelic compound that belongs to the NBOMe class of phenethylamines. It is a derivative of the 2C family of psychedelics, specifically 2C-B, and is known for its potent hallucinogenic effects.

Chemical Structure and Properties

25B-NB4OMe is chemically related to 2C-B, with the addition of a 4-methoxybenzyl group to the nitrogen atom. This modification increases its affinity for the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. The compound has a molecular formula of C₁₈H₂₂BrNO₃ and a molecular weight of 380.28 g/mol.

Pharmacology

25B-NB4OMe acts primarily as a partial agonist at the 5-HT2A receptor, similar to other compounds in the NBOMe series. This receptor is a subtype of the serotonin receptor and is implicated in the modulation of mood, perception, and cognition. The binding of 25B-NB4OMe to this receptor is thought to lead to the characteristic psychedelic effects, including visual and auditory hallucinations, altered sense of time, and changes in thought patterns.

Effects

The effects of 25B-NB4OMe are similar to those of other NBOMe compounds and can include:

• Visual hallucinations: Users report vivid and colorful visual patterns, distortions, and enhancements.
• Altered perception: Changes in the perception of time, space, and self.
• Euphoria: A sense of well-being and happiness.
• Cognitive effects: Altered thought processes, introspection, and philosophical thinking.

Risks and Safety

The use of 25B-NB4OMe carries significant risks, particularly due to its potency and the potential for overdose. Adverse effects can include:

• Cardiovascular issues: Increased heart rate and blood pressure.
• Psychological distress: Anxiety, paranoia, and confusion.
• Toxicity: At high doses, there is a risk of severe toxicity, which can be life-threatening.

Legal Status

The legal status of 25B-NB4OMe varies by country. In many jurisdictions, it is not specifically controlled, but it may fall under analog laws that regulate substances similar to controlled drugs.

History and Research

25B-NB4OMe was first synthesized in the early 21st century as part of research into the structure-activity relationships of phenethylamines. It has been used in scientific studies to better understand the role of the 5-HT2A receptor in psychedelic experiences.

Also see

• NBOMe
• 2C-B
• Psychedelic drug
• Serotonin receptor