Difluoroescaline

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A detailed overview of Difluoroescaline, a psychedelic compound



Difluoroescaline (2,4-difluoro-5-ethoxyphenethylamine) is a synthetic psychedelic compound belonging to the phenethylamine class. It is structurally related to mescaline, a naturally occurring psychedelic found in the peyote cactus, but with two fluorine atoms replacing hydrogen atoms on the aromatic ring.

Chemical Structure and Properties[edit | edit source]

Difluoroescaline is a derivative of escaline, which itself is a derivative of mescaline. The chemical structure of difluoroescaline includes a phenethylamine backbone with an ethoxy group at the 4-position and two fluorine atoms at the 2- and 5-positions of the aromatic ring. This modification is thought to influence the compound's pharmacological properties.

Molecular Formula: C11H15F2NO

Molecular Weight: 215.24 g/mol

Pharmacology[edit | edit source]

The pharmacological effects of difluoroescaline are not well-documented, but it is presumed to act as a serotonin receptor agonist, similar to other phenethylamine psychedelics. The presence of fluorine atoms may alter its binding affinity and metabolic stability compared to its non-fluorinated analogs.

Effects[edit | edit source]

The subjective effects of difluoroescaline are largely anecdotal and may include:

  • Visual Distortions: Users report enhanced colors and patterns.
  • Altered Perception: Changes in the perception of time and space.
  • Emotional Effects: Euphoria and emotional introspection.

Legal Status[edit | edit source]

Difluoroescaline is not specifically scheduled under the Controlled Substances Act in the United States, but it may be considered an analog of a controlled substance under the Federal Analogue Act. Its legal status may vary in other countries.

Safety and Toxicity[edit | edit source]

There is limited data on the safety and toxicity of difluoroescaline. As with other research chemicals, caution is advised due to the lack of comprehensive studies on its effects and potential risks.

History and Research[edit | edit source]

Difluoroescaline was first synthesized in the early 21st century as part of research into novel psychedelics. It has been studied primarily in vitro and in animal models, with limited human use reported in the literature.

Also see[edit | edit source]



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