25D-NB4OMe

A synthetic psychedelic compound

25D-NB4OMe is a synthetic psychedelic compound that belongs to the NBOMe class of drugs. It is a derivative of the phenethylamine 2C-D, modified with a 4-methoxybenzyl group. This compound is known for its potent agonistic activity at the 5-HT2A receptor, which is primarily responsible for its psychedelic effects.

Chemical Structure and Properties

25D-NB4OMe is chemically classified as a phenethylamine, with the IUPAC name 2-(4-Iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine. The presence of the iodine atom at the 4-position of the phenyl ring and the methoxy groups at the 2 and 5 positions are characteristic of the NBOMe series. The compound has a molecular weight of 427.28 g/mol.

Pharmacology

25D-NB4OMe acts primarily as a potent agonist at the 5-HT2A receptor, which is a subtype of the serotonin receptor. This receptor is known to play a significant role in the modulation of mood, perception, and cognition, and its activation is associated with the psychedelic effects of compounds like LSD and psilocybin. The NBOMe compounds, including 25D-NB4OMe, are known for their high affinity and selectivity for the 5-HT2A receptor.

Effects

The effects of 25D-NB4OMe are similar to those of other psychedelics, including altered perception of time and space, visual hallucinations, and changes in thought patterns. Users may experience enhanced sensory perception, emotional shifts, and a sense of euphoria. However, the intensity and duration of these effects can vary significantly depending on the dose and individual sensitivity.

Risks and Safety

As with other NBOMe compounds, 25D-NB4OMe can pose significant risks, particularly at higher doses. Adverse effects may include vasoconstriction, tachycardia, hypertension, and hyperthermia. There have been reports of severe toxicity and fatalities associated with the use of NBOMe compounds, often due to overdose or misidentification of the substance.

Legal Status

The legal status of 25D-NB4OMe varies by country. In some jurisdictions, it may be classified as a controlled substance, while in others it may remain unregulated. Users should be aware of the legal implications of possessing or distributing this compound in their region.

Also see

• NBOMe series
• 2C-D
• 5-HT2A receptor
• Psychedelic drug

Receptor Ligands
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Class	Not specified
Function	Not specified
Endogenous Ligands	None listed
Agonists	None listed
Antagonists	None listed
Partial Agonists	None listed
Inverse Agonists	None listed
Allosteric Modulators	None listed
Related Receptors	None listed