2C-NH2

A chemical compound related to the phenethylamine class

2C-NH2 is a chemical compound that belongs to the phenethylamine class. It is structurally related to the 2C family of psychedelic phenethylamines, which includes compounds such as 2C-B and 2C-I.

Chemical Structure and Properties

2C-NH2 is characterized by the presence of a 2,5-dimethoxyphenyl group attached to an ethanamine backbone. The chemical formula for 2C-NH2 is C₁₀H₁₅NO₂, and it has a molecular weight of 181.23 g/mol.

The compound is a derivative of phenethylamine, with methoxy groups at the 2 and 5 positions of the benzene ring. This structural modification is common among the 2C series, which are known for their psychoactive properties.

Pharmacology

The pharmacological properties of 2C-NH2 are not well-documented in the scientific literature. However, based on its structural similarity to other 2C compounds, it is hypothesized to act as a serotonin receptor agonist, particularly at the 5-HT_2A receptor. This receptor is known to play a significant role in the effects of psychedelic substances.

Synthesis

The synthesis of 2C-NH2 typically involves the reaction of 2,5-dimethoxybenzaldehyde with nitroethane to form a nitrostyrene intermediate. This intermediate is then reduced to the corresponding amine using a reducing agent such as lithium aluminum hydride (LAH).

Legal Status

As of the current date, the legal status of 2C-NH2 is not explicitly defined in many jurisdictions. However, due to its structural similarity to other controlled substances in the 2C family, it may be considered a controlled substance under analogue laws in certain countries.

Research and Applications

Research on 2C-NH2 is limited, and it is primarily of interest in the field of psychopharmacology for its potential psychoactive effects. It is not approved for medical use and is typically studied in a laboratory setting.

Also see

• 2C-B
• 2C-I
• Phenethylamine
• Psychedelic drug
• Serotonin receptor